• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

实验性口腔黏膜致癌过程中的上皮-间充质相互作用：建立一种技术。

Epithelial-mesenchymal interactions in experimental oral mucosal carcinogenesis: establishing a technique.

作者信息

Rich A M, Reade P C

机构信息

Section of Oral Medicine and Oral Surgery, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Victoria, Australia.

出版信息

Int J Exp Pathol. 1992 Jun;73(3):359-69.

PMID:1622846
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2002346/
Abstract

The carcinogen 4-nitroquinoline-1-oxide was applied to the palatal mucosa of rats for varying periods of time. This tissue was separated into epithelial and connective components and then recombined in various combinations and implanted into hypothymic mice. Seventy-two per cent of the implants were recovered and were suitable for detailed histological analysis. The technique provides a suitable model for the assessment of epithelial-connective tissue interactions in experimental oral mucosal carcinogenesis.

摘要

将致癌物4-硝基喹啉-1-氧化物应用于大鼠的腭黏膜不同时间段。将该组织分离为上皮和结缔组织成分，然后以各种组合重新组合并植入无胸腺小鼠体内。72%的植入物被回收且适合进行详细的组织学分析。该技术为评估实验性口腔黏膜致癌过程中的上皮-结缔组织相互作用提供了一个合适的模型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6907/2002346/b0d6fd0f6390/ijexpath00021-0102-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6907/2002346/e1c803378802/ijexpath00021-0097-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6907/2002346/d22f6a50f650/ijexpath00021-0097-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6907/2002346/bb4c7febb1df/ijexpath00021-0098-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6907/2002346/3bd388cf0235/ijexpath00021-0099-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6907/2002346/bc4dbebc990c/ijexpath00021-0099-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6907/2002346/864522c568fd/ijexpath00021-0100-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6907/2002346/0da990f996b1/ijexpath00021-0100-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6907/2002346/821995a441ec/ijexpath00021-0101-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6907/2002346/2f0f4931f4ae/ijexpath00021-0101-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6907/2002346/b5b5a8c782db/ijexpath00021-0102-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6907/2002346/b0d6fd0f6390/ijexpath00021-0102-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6907/2002346/e1c803378802/ijexpath00021-0097-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6907/2002346/d22f6a50f650/ijexpath00021-0097-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6907/2002346/bb4c7febb1df/ijexpath00021-0098-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6907/2002346/3bd388cf0235/ijexpath00021-0099-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6907/2002346/bc4dbebc990c/ijexpath00021-0099-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6907/2002346/864522c568fd/ijexpath00021-0100-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6907/2002346/0da990f996b1/ijexpath00021-0100-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6907/2002346/821995a441ec/ijexpath00021-0101-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6907/2002346/2f0f4931f4ae/ijexpath00021-0101-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6907/2002346/b5b5a8c782db/ijexpath00021-0102-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6907/2002346/b0d6fd0f6390/ijexpath00021-0102-b.jpg

相似文献

1
Epithelial-mesenchymal interactions in experimental oral mucosal carcinogenesis: establishing a technique.实验性口腔黏膜致癌过程中的上皮-间充质相互作用：建立一种技术。
Int J Exp Pathol. 1992 Jun;73(3):359-69.
2
Epithelial-mesenchymal interactions in experimental oral mucosal carcinogenesis.
J Oral Pathol Med. 2001 Aug;30(7):389-97. doi: 10.1034/j.1600-0714.2001.300702.x.
3
The effect of topical vitamin C on palatal oral mucosal carcinogenesis using 4-nitroquinoline-1-oxide.局部应用维生素C对4-硝基喹啉-1-氧化物诱导的腭部口腔黏膜癌变的影响
J Biol Buccale. 1991 Sep;19(3):199-204.
4
Histomorphometric analysis of epithelial changes in chemically induced oral mucosal carcinogenesis in rats.大鼠化学诱导口腔黏膜癌变过程中上皮变化的组织形态计量学分析
J Oral Pathol. 1988 Nov;17(9-10):528-33. doi: 10.1111/j.1600-0714.1988.tb01329.x.
5
Induction by 4-nitroquinoline-1-oxide of oral epithelial dysplasia and neoplasia in scurvy-prone osteogenic disorder Shionogi (ODS) rats.
Nutr Cancer. 1996;26(1):83-90. doi: 10.1080/01635589609514465.
6
Basal cell nuclear size in experimental oral mucosal carcinogenesis.实验性口腔黏膜致癌过程中的基底细胞核大小
Br J Cancer. 1991 Jul;64(1):96-8. doi: 10.1038/bjc.1991.248.
7
Epithelial dysplasia and squamous cell carcinoma of the Wistar rat palatal mucosa: 4NQO model.Wistar大鼠腭黏膜上皮发育异常和鳞状细胞癌：4-硝基喹啉-1-氧化物模型
Head Neck. 1996 Sep-Oct;18(5):441-9. doi: 10.1002/(SICI)1097-0347(199609/10)18:5<441::AID-HED7>3.0.CO;2-5.
8
Oral mucosal carcinogenesis in SENCAR mice.SENCAR小鼠的口腔黏膜致癌作用
Anticancer Res. 2002 Sep-Oct;22(5):2733-40.
9
[Effect of connective tissues underlying precancerous lesions combined with epithelia separated from normal mucosa].[癌前病变下方结缔组织联合从正常黏膜分离的上皮的作用]
Zhonghua Kou Qiang Yi Xue Za Zhi. 1992 Sep;27(5):266-9, 318.
10
Epithelial dendritic cells and connective tissue macrophages in oral carcinogenesis and the effects of systemic Corynebacterium parvum.口腔癌发生过程中的上皮树突状细胞和结缔组织巨噬细胞以及全身性短小棒状杆菌的作用
Carcinogenesis. 1989 Mar;10(3):501-7. doi: 10.1093/carcin/10.3.501.

本文引用的文献

1
Connective tissue influences on patterns of epithelial architecture and keratinization in skin and oral mucosa of the adult mouse.结缔组织对成年小鼠皮肤和口腔黏膜上皮结构模式及角化的影响。
Cell Tissue Res. 1984;235(3):551-9. doi: 10.1007/BF00226952.
2
Normal keratinized mucosa transplants in nude mice.裸鼠中的正常角化黏膜移植
Acta Odontol Scand. 1981;39(4):187-93. doi: 10.3109/00016358109162279.
3
Oral leukoplakia transplanted to nude mice.移植到裸鼠体内的口腔白斑。
Scand J Dent Res. 1981 Jun;89(3):275-82. doi: 10.1111/j.1600-0722.1981.tb01683.x.
4
Histomorphometric analysis of epithelial changes in chemically induced oral mucosal carcinogenesis in rats.大鼠化学诱导口腔黏膜癌变过程中上皮变化的组织形态计量学分析
J Oral Pathol. 1988 Nov;17(9-10):528-33. doi: 10.1111/j.1600-0714.1988.tb01329.x.
5
A method for studying epithelial-mesenchymal interactions in human oral mucosal lesions.一种研究人类口腔黏膜病变中上皮-间充质相互作用的方法。
Scand J Dent Res. 1979 Jun;87(3):234-43. doi: 10.1111/j.1600-0722.1979.tb00677.x.