Rich A M, Reade P C
Department of Dental Medicine and Surgery, University of Melbourne, Australia.
J Oral Pathol. 1988 Nov;17(9-10):528-33. doi: 10.1111/j.1600-0714.1988.tb01329.x.
Quantitative analysis of rat palatal mucosa after the carcinogen 4- nitroquinoline-1-oxide had been applied to the epithelium for varying periods of time showed that there was a significant increase in epithelial thickness, due largely to an increase in thickness of the basal compartment. This alteration was measurable before epithelial dysplasia could be recognised.
对用致癌物4-硝基喹啉-1-氧化物作用于大鼠腭黏膜上皮不同时间段后的组织进行定量分析，结果显示上皮厚度显著增加，这主要是由于基底细胞层厚度增加所致。这种改变在能够识别上皮发育异常之前就可以检测到。
