Bouchon R, Griebel G, Vogel E, Misslin R, Ropartz P
Laboratoire de Psychophysiologie, URA-CNRS, Université Louis Pasteur, Strasbourg, France.
Neuroreport. 1992 Feb;3(2):210-2. doi: 10.1097/00001756-199202000-00023.
The effects of ovine prolactin (PRL) (2 x 5 IU a day) and an ectopic pituitary isograft on the responsiveness were examined using locomotor and exploratory activities as measures in PRL-growth-hormone-thyrotropin-deficient Snell dwarf mice (dw/dw). After 5 weeks of treatment, both PRL and the graft restored the two behavioural measures to normal levels. Results clearly demonstrate the involvement of PRL in global behavioural responsiveness and suggest a possible role for PRL in the changes induced by the graft.
以运动和探索活动为指标，研究了绵羊催乳素（PRL）（每天2×5国际单位）和异位垂体同种异体移植物对PRL-生长激素-促甲状腺激素缺乏的斯内尔侏儒小鼠（dw/dw）反应性的影响。治疗5周后，PRL和移植物均使这两种行为指标恢复到正常水平。结果清楚地表明PRL参与了整体行为反应，并提示PRL在移植物诱导的变化中可能发挥作用。
