Bouchon R, Ropartz P
Laboratoire de Psychophysiologie, URA CNRS 1295, Université Louis Pasteur, Strasbourg, France.
Physiol Behav. 1990 Oct;48(4):501-5. doi: 10.1016/0031-9384(90)90290-k.
The effects of ectopic pituitary isograft implanted in 13- or 21-day-old Snell dwarf mice on their freely expressed behavior were examined over a 14- or 31-day period. This mutant strain has severe anterohypophyseal deficiency which causes high levels of inactivity and abnormally low exploratory activity. The graft totally normalized these behaviors. Results showed that the time necessary for inducing behavioral changes is independent of age of the animals at the time of grafting, but the age at which implantation occurs influences the speed of full behavioral normalization. The possible involvement of prolactin and growth hormone in such behavioral improvement is discussed.
在14天或31天的时间里，研究了将异位垂体同种异体移植到13日龄或21日龄的斯内尔侏儒小鼠体内对其自由表达行为的影响。这种突变品系存在严重的垂体前叶功能缺陷，导致活动水平高和探索活动异常低。移植使这些行为完全恢复正常。结果表明，诱导行为改变所需的时间与移植时动物的年龄无关，但移植发生时的年龄会影响行为完全恢复正常的速度。文中还讨论了催乳素和生长激素可能参与这种行为改善的情况。
