Heidmann J, Poulsen S, Arnbjerg D, Kirkegaard E, Laurberg L
Department of Child Dental Health, Royal Dental College, Aarhus, Denmark.
Community Dent Oral Epidemiol. 1992 Jun;20(3):118-21. doi: 10.1111/j.1600-0528.1992.tb01543.x.
In a municipality near Copenhagen, Denmark, where fortnightly fluoride rinses with 0.2% neutral sodium fluoride had been performed for more than a decade, 1306 children from kindergarten through 6th grade were stratified by school and grade and randomly distributed into two groups. One group continued the fluoride rinses, the other group had the fluoride solution replaced with distilled water. Both solutions were slightly flavored. 1083 children completed the 3-yr trial. Caries was recorded clinically by the dentists in the municipal dental service using the diagnostic criteria for the Child Dental Health Services, and on bitewing radiographs by one of the authors applying the criteria developed by GRONDAHL et al. Permanent molars and premolars were included in the study. Clinically, caries increment in the two groups was the same with pits and fissures containing 94% of the DMFS. According to the radiographs, caries progression in the water group was higher than in the fluoride group. This difference was statistically significant for the surfaces erupting during the study (P less than 0.05).
在丹麦哥本哈根附近的一个自治市,超过十年来每两周用0.2%的中性氟化钠进行一次氟化物漱口,1306名从幼儿园到六年级的儿童按学校和年级分层,并随机分为两组。一组继续进行氟化物漱口,另一组将氟化物溶液换成蒸馏水。两种溶液都加了一点味道。1083名儿童完成了为期3年的试验。市牙科服务机构的牙医根据儿童牙科保健服务的诊断标准对龋齿进行临床记录,一位作者根据格伦达尔等人制定的标准在咬合翼片上进行记录。恒牙磨牙和前磨牙被纳入研究。临床上,两组龋齿增加情况相同,窝沟龋占DMFS的94%。根据X光片,用水组的龋齿进展高于用氟组。对于研究期间萌出的表面,这种差异具有统计学意义(P小于0.05)。