Quirinia A, Jensen F T, Viidik A
Department of Connective Tissue Biology, University of Aarhus, Denmark.
Scand J Plast Reconstr Surg Hand Surg. 1992;26(1):21-8. doi: 10.3109/02844319209035178.
A standardized ischemic, H-shaped, double flap model in rats was developed for investigating the influence of different factors that could potentially increase flap survival. The blood flow was measured in the flaps as well as in normal healing incisional wounds on day -1 (intact skin) and on days 1, 4, 8, and 16 by the xenon-133 (133Xe) clearance technique. The flow in normal healing incisional wounds remained the same as the flow in intact skin. The flow in the flaps, however, initially decreased to ischemic levels, but afterwards gradually increased to that of normal healing incisional wounds and intact skin. Further, the cutaneous blood flow in both the cranially and the caudally based ischemic dorsal flap was independent of the width of the flap.
为研究可能提高皮瓣存活率的不同因素的影响，建立了一种标准化的大鼠缺血性H形双皮瓣模型。在第-1天（完整皮肤）以及第1、4、8和16天，通过氙-133（133Xe）清除技术测量皮瓣以及正常愈合切口伤口的血流量。正常愈合切口伤口的血流量与完整皮肤的血流量保持相同。然而，皮瓣中的血流量最初降至缺血水平，但随后逐渐增加至正常愈合切口伤口和完整皮肤的血流量。此外，基于头部和尾部的缺血性背部皮瓣中的皮肤血流量与皮瓣宽度无关。
