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微波辅助合成新型 2,3-二氢-4-吡啶酮。

Microwave-assisted synthesis of novel 2,3-dihydro-4-pyridinones.

机构信息

Department of Chemistry, College of Education, University of Basrah, Iraq.

出版信息

Molecules. 2010 Nov 17;15(11):8425-30. doi: 10.3390/molecules15118425.

DOI:10.3390/molecules15118425
PMID:21085086
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6259262/
Abstract

Novel 2,3-dihydro-4-pyridinones were synthesized via the reaction of curcumin and primary amines or amine acetates under microwave irradiation. Montmorillonite K-10 was used as a catalyst. Reaction times did not exceed 120 s. The structures of the compounds were established by elemental analysis and from their mass, 1H- and 13C-NMR spectra.

摘要

新型 2,3-二氢-4-吡啶酮通过姜黄素与伯胺或胺乙酸盐在微波辐射下的反应合成。蒙脱土 K-10 用作催化剂。反应时间不超过 120 秒。通过元素分析和它们的质谱、1H-NMR 和 13C-NMR 谱确定了化合物的结构。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d23/6259262/c313d809a77e/molecules-15-08425-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d23/6259262/c313d809a77e/molecules-15-08425-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d23/6259262/c313d809a77e/molecules-15-08425-g001.jpg

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本文引用的文献

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Org Lett. 2009 Dec 3;11(23):5562-5. doi: 10.1021/ol902402v.
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2,3-Dihydro-4H-pyran-4-ones and 2,3-dihydro-4-pyridinones by cyclizations of alpha,beta-unsaturated 1,3-diketones.α,β-不饱和 1,3-二酮的环化反应生成 2,3-二氢-4H-吡喃-4-酮和 2,3-二氢-4-吡啶酮。
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