Power Daniel A, Burton Jeremy P, Chilcott Chris N, Tagg John R, Dawes Patrick J
Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.
J Clin Microbiol. 2005 Nov;43(11):5822-4. doi: 10.1128/JCM.43.11.5822-5824.2005.
Middle meatus aspirates from patients with chronic rhinosinusitis were analyzed by bacterial culture, denaturing gradient gel electrophoresis (DGGE), and antibiotic sensitivity techniques. DGGE detected a greater bacterial diversity than culture methods. Although resistance to antibiotics was low, there was evidence of changes in the composition of the bacterial microbiota over time, and the presence of noncultured bacteria was demonstrated.
通过细菌培养、变性梯度凝胶电泳(DGGE)和抗生素敏感性技术对慢性鼻窦炎患者的中鼻道吸出物进行了分析。DGGE检测到的细菌多样性比培养方法更多。尽管对抗生素的耐药性较低,但有证据表明随着时间推移细菌微生物群的组成发生了变化,并且证实了未培养细菌的存在。