Shlipak Michael, Stehman-Breen Catherine
General Internal Medicine Section, Veterans Affairs Medical Center, and Departments of Medicine, Epidemiology, and Biostatistics, University of California, San Francisco, San Francisco, California, USA.
J Am Soc Nephrol. 2005 Dec;16(12):3477-84. doi: 10.1681/ASN.2005080806. Epub 2005 Nov 9.
Observational, patient-oriented research is a term that describes clinical or community-based studies in that they do not involve an experiment or intervention. Observational research studies can be designed and implemented by a primary data collection or using previously collected patient data. The latter is less expensive, although it has some distinct limitations. Many research databases are readily available and can be used to answer important questions that are relevant to kidney disease. This review summarizes the types of research analyses that can be conducted using existing databases, the types of research databases available, and a general approach for addressing a proposed research question using existing data.
以患者为导向的观察性研究是一个术语，用于描述基于临床或社区的研究，因为它们不涉及实验或干预。观察性研究可以通过收集原始数据或使用先前收集的患者数据来设计和实施。后者成本较低，尽管有一些明显的局限性。许多研究数据库很容易获取，可用于回答与肾脏疾病相关的重要问题。本综述总结了使用现有数据库可进行的研究分析类型、可用的研究数据库类型以及使用现有数据解决拟议研究问题的一般方法。
