Kremers Hilal Maradit
Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA.
Bull NYU Hosp Jt Dis. 2009;67(2):193-7.
Observational studies, administrative database studies, and registries offer a wealth of real-world information, if designed, maintained, and analyzed according to appropriate observational study methodology. This review summarizes basic observational study methods employed in rheumatology and highlights several notable examples. In response to growing interest in real-world effectiveness and safety data, registries are expected to proliferate in the near future. The availability of detailed clinical information in registries coupled with powerful tools for analysis offers promise for timely and accurate information on the safety and effectiveness of rheumatic treatments.
观察性研究、行政数据库研究和登记处提供了丰富的真实世界信息，前提是按照适当的观察性研究方法进行设计、维护和分析。本综述总结了风湿病学中使用的基本观察性研究方法，并重点介绍了几个显著的例子。鉴于对真实世界有效性和安全性数据的兴趣日益浓厚，预计登记处在不久的将来会大量增加。登记处提供的详细临床信息以及强大的分析工具，有望及时、准确地提供有关风湿性疾病治疗安全性和有效性的信息。
