Brunning R D, Parkin J
Am J Pathol. 1975 Jan;78(1):59-70.
Parallel tubular inclusions were found in peripheral blood lymphocytes from 18 patients with various hematologic disorders, primarily lymphoproliferative processes, and 1 apparently healthy individual. The inclusions varied in size from 1000 to 6000 A and were usually membrane bounded. The microtubule-like structures comprising the inclusions ranged in size from 150 to 300 A and were packed in wall-to-wall contact with each other. Dense amorphous material and small dark crystalloids were frequently noted in the inclusions. There appeared to be a spatial and structural relationship of the inclusions with the centriole. The highest percent of lymphocytes with inclusionss (greater than 90%) were found in a patient with a lympho-proliferative disorder in whom 95% of the peripheral blood lymphocytes typed as T cells by spontaneous rosette formation with sheep red blood cells. (Am J Pathol 78:59-70, 1975)
在18例患有各种血液系统疾病（主要是淋巴细胞增殖性疾病）的患者以及1名看似健康的个体的外周血淋巴细胞中发现了平行管状包涵体。这些包涵体大小从1000到6000埃不等，通常有膜包被。构成包涵体的微管样结构大小从150到300埃不等，彼此紧密排列。在包涵体中经常可见致密的无定形物质和小的深色晶体。包涵体与中心粒之间似乎存在空间和结构上的关系。在一名淋巴细胞增殖性疾病患者中发现含包涵体的淋巴细胞比例最高（超过90%），该患者外周血淋巴细胞中有95%通过与绵羊红细胞自发形成玫瑰花结而被鉴定为T细胞。（《美国病理学杂志》78:59 - 70, 1975）
