Kobayashi Hideo, Sugimoto Chikatoshi, Kanoh Soichiro, Motoyoshi Kazuo, Aida Shinsuke
Third Department of Medicine, National Defense Medical College, Saitama, Japan.
J Thorac Imaging. 2005 Nov;20(4):291-3. doi: 10.1097/01.rti.0000168600.78213.85.
A 55-year-old man complained of cough and dyspnea. His chest radiograph and CT scan revealed a solitary nodule with a diameter of 2 cm, which showed an air bronchogram and had a hazy contour. After 3 weeks, the radiologic findings changed to diffuse infiltration with small centrilobular nodules, alveolar consolidation, and bronchial wall thickening. The alveoli contained numerous fibrin balls and organizing tissue, which are typical pathologic features of acute fibrinous and organizing pneumonia (AFOP), on histologic examination. We report the initial radiologic features of AFOP and suggest that there are some radiologic similarities between this condition and cryptogenic organizing pneumonia.
一名55岁男性主诉咳嗽和呼吸困难。他的胸部X线片和CT扫描显示一个直径2厘米的孤立结节,该结节显示空气支气管征且轮廓模糊。3周后,影像学表现变为弥漫性浸润,伴有小叶中心性小结节、肺泡实变和支气管壁增厚。组织学检查显示肺泡内有大量纤维蛋白球和机化组织,这是急性纤维蛋白性和机化性肺炎(AFOP)的典型病理特征。我们报告了AFOP的初始影像学特征,并提示该疾病与隐源性机化性肺炎在影像学上存在一些相似之处。