Lamminen A E, Tanttu J I, Sepponen R E, Suramo I J, Pihko H
Department of Diagnostic Radiology, University Central Hospital, Helsinki, Finland.
Br J Radiol. 1990 Aug;63(752):591-6. doi: 10.1259/0007-1285-63-752-591.
Magnetic resonance examinations of skeletal muscle with differential T1 relaxation time measurements were performed in 19 patients with muscular dystrophies and congenital myopathies, and in eight control subjects. A field echo chemical shift imaging technique was used. T1 values of muscular tissue were measured from the primary composite images, and differential T1 values were calculated separately from water and fat images. Longitudinal relaxation times of skeletal muscle were significantly increased in both dystrophies and myopathies. The results of differential relaxation time measurements suggest that intramuscular fat reduces the abnormal increase in T1 of diseased muscle tissue. When characterizing diseases of skeletal muscle by T1 relaxation time measurements, the contribution of secondary fatty infiltration must be considered.
对19例肌肉营养不良症和先天性肌病患者以及8名对照者进行了采用不同T1弛豫时间测量的骨骼肌磁共振检查。使用了场回波化学位移成像技术。从原始复合图像测量肌肉组织的T1值，并分别从水图像和脂肪图像计算差异T1值。在肌肉营养不良症和肌病中，骨骼肌的纵向弛豫时间均显著增加。差异弛豫时间测量结果表明，肌内脂肪减少了患病肌肉组织T1的异常增加。在通过T1弛豫时间测量来表征骨骼肌疾病时，必须考虑继发性脂肪浸润的影响。
