Sharma Anu, Martin Kathryn, Roland Peter, Bauer Paul, Sweeney Melissa H, Gilley Phillip, Dorman Michael
Behavioral and Brian Sciences, Callier Advanced Hearing Research Center, University of Texas at Dallas 75235, USA.
J Am Acad Audiol. 2005 Sep;16(8):564-73. doi: 10.3766/jaaa.16.8.5.
We used the latency of the P1 cortical auditory-evoked potential (CAEP) as a biomarker for the development of central auditory pathways in three children who received intervention through hearing aids and/or cochlear implants. Our goal was to examine the clinical feasibility of using the latency of the P1 CAEP as an objective tool to evaluate whether acoustic amplification for hearing-impaired children has provided sufficient stimulation for normal development of central auditory pathways. If clinicians have such a marker, then they can more confidently make a decision about whether to provide a child with a cochlear implant following an appropriate hearing-aid trial. Using the same marker, clinicians will also be able to monitor the maturation of central auditory pathways once electrical stimulation is initiated.
我们将三名通过助听器和/或人工耳蜗接受干预的儿童的P1皮质听觉诱发电位（CAEP）潜伏期作为中枢听觉通路发育的生物标志物。我们的目标是检验将P1 CAEP潜伏期作为一种客观工具的临床可行性，以评估对听力受损儿童进行的声音放大是否为中枢听觉通路的正常发育提供了足够的刺激。如果临床医生有这样一个标志物，那么他们就能更有信心地决定在进行适当的助听器试验后是否为儿童植入人工耳蜗。使用同一个标志物，一旦开始电刺激，临床医生还能够监测中枢听觉通路的成熟情况。
