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西孟加拉邦农村青光眼患病率及类型的基于人群的调查:西孟加拉邦青光眼研究

A population based survey of the prevalence and types of glaucoma in rural West Bengal: the West Bengal Glaucoma Study.

作者信息

Raychaudhuri A, Lahiri S K, Bandyopadhyay M, Foster P J, Reeves B C, Johnson G J

机构信息

Department of Public Health and Policy, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.

出版信息

Br J Ophthalmol. 2005 Dec;89(12):1559-64. doi: 10.1136/bjo.2005.074948.

Abstract

AIM

To determine (i) the prevalence of glaucoma in people aged > or =50 years, (ii) the proportions of different types of glaucoma, (iii) the distributions of intraocular pressure and vertical cup disc ratio.

METHOD

Population based prevalence survey in rural West Bengal. People aged > or =50 years in randomly selected villages in 24 Parganas South district. The main outcome measures were diagnosis of glaucoma, based on criteria described by the International Society for Geographic and Epidemiological Ophthalmology.

RESULTS

1594 people aged > or =50 years were enumerated in nine villages; 1324 (83.1%) were surveyed and 1269 people adequately examined. 42 definite cases of glaucoma were identified, with prevalence increasing from 2.7% (95% CI 1.7 to 3.7) in people aged 50-59 years to 6.5% (95% CI 0.0 to 14.1) in those aged > or =80 years. The age standardised estimate for the prevalence of all glaucoma in people aged > or =50 years was 3.4%. Only three cases of primary angle closure glaucoma (PACG) were identified, giving a crude ratio of primary open angle glaucoma (POAG) to PACG of more than 10:1. Three people with glaucoma were blind in one eye but none was blind in both eyes.

CONCLUSION

Compared to other surveys of glaucoma in India, the age standardised prevalence observed was less than in Hyderabad, but similar to Tamil Nadu and Dhaka. The ratio of POAG to PACG was much higher than found previously, suggesting that PACG may be less prevalent in Bengalis than in Indian populations living in south India. The authors conclude that ophthalmic services in West Bengal should focus on detecting POAG. Since there is still no satisfactory method of screening for POAG, there is no alternative to case detection (opportunistic screening) in eye clinics.

摘要

目的

确定(i)年龄≥50岁人群中青光眼的患病率,(ii)不同类型青光眼的比例,(iii)眼压和垂直杯盘比的分布情况。

方法

在西孟加拉邦农村地区进行基于人群的患病率调查。在南24帕加纳斯区随机选取村庄中年龄≥50岁的人群。主要观察指标是根据国际地理和流行病学眼科学会描述的标准诊断青光眼。

结果

在9个村庄中确定了1594名年龄≥50岁的人;对1324人(83.1%)进行了调查,对1269人进行了充分检查。确定了42例确诊青光眼病例,患病率从50 - 59岁人群中的2.7%(95%可信区间1.7至3.7)增至80岁及以上人群中的6.5%(95%可信区间0.0至14.1)。年龄≥50岁人群中所有青光眼患病率的年龄标准化估计值为3.4%。仅发现3例原发性闭角型青光眼(PACG)病例,原发性开角型青光眼(POAG)与PACG的粗略比例超过10:1。3例青光眼患者单眼失明,但无双眼失明者。

结论

与印度其他青光眼调查相比,观察到的年龄标准化患病率低于海得拉巴,但与泰米尔纳德邦和达卡相似。POAG与PACG的比例远高于先前发现的比例,表明孟加拉人患PACG的可能性可能低于居住在印度南部的印度人群。作者得出结论,西孟加拉邦的眼科服务应侧重于检测POAG。由于目前仍没有令人满意的POAG筛查方法,在眼科诊所进行病例发现(机会性筛查)是唯一的选择。

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本文引用的文献

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Global data on visual impairment in the year 2002.2002年全球视力损害数据。
Bull World Health Organ. 2004 Nov;82(11):844-51. Epub 2004 Dec 14.
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Glaucoma in southern India.印度南部的青光眼
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