Rahman M M, Rahman N, Foster P J, Haque Z, Zaman A U, Dineen B, Johnson G J
Department of Epidemiology, Institute of Ophthalmology, Bath Street, London EC1V 9EL, UK.
Br J Ophthalmol. 2004 Dec;88(12):1493-7. doi: 10.1136/bjo.2004.043612.
BACKGROUND/AIM: Few studies have reported on the epidemiology and clinical characteristics of glaucoma in south Asia. This project aimed to determine the prevalence of glaucoma of Dhaka, Bangladesh.
A multistage, stratified, clustered sample was drawn from Dhaka Division, Bangladesh, using systematic sampling to identify individual subjects aged 35 years and older. Examination of all subjects included Snellen visual acuity, slit lamp examination (including gonioscopy and applanation tonometry) and a stereoscopic assessment of the vertical cup:disc ratio (CDR). In selected subjects, a threshold visual field examination was performed. Glaucoma was diagnosed on the basis of statistical abnormality of the vertical CDR combined with an abnormal visual field test, or in subjects with advanced glaucoma who could not complete field testing, a grossly abnormal CDR. If it was not possible to examine the optic discs and the subject was blind, glaucoma was diagnosed on the basis of a raised intraocular pressure.
Of 3562 eligible subjects, 2347 were examined (66%). Among people aged 40 years and older, the prevalence of definite glaucoma was 2.1% (95% confidence interval: 1.5 to 2.9; 39 people). The prevalence of definite and probable glaucoma was 3.1% (95% CI: 2.4 to 4.0; 58 people) in subjects of the same age. Primary open angle glaucoma was the most common form of glaucoma, accounting for 75% of the total. Among cases of blindness not attributable to refractive error, 5% were caused by glaucoma. Glaucoma prevalence was higher in men than women, but did not show the typical increase with age.
Glaucoma prevalence is relatively high in Bangladesh, although it accounts for only a small proportion of blindness in the community. It is estimated that there are approximately 586 000 people 40 years and older with definite or probable glaucoma in Bangladesh.
背景/目的:关于南亚青光眼的流行病学和临床特征的研究报道较少。本项目旨在确定孟加拉国达卡市青光眼的患病率。
采用系统抽样方法,从孟加拉国达卡专区抽取多阶段、分层、整群样本,以确定35岁及以上的个体。对所有受试者进行的检查包括斯内伦视力检查、裂隙灯检查(包括前房角镜检查和压平眼压测量)以及垂直杯盘比(CDR)的立体评估。对选定的受试者进行阈值视野检查。青光眼的诊断基于垂直CDR的统计学异常并伴有异常视野检查结果,或者对于无法完成视野检查的晚期青光眼患者,基于明显异常的CDR。如果无法检查视盘且受试者失明,则根据眼压升高诊断青光眼。
在3562名符合条件的受试者中,2347人接受了检查(66%)。在40岁及以上人群中,确诊青光眼的患病率为2.1%(95%置信区间:1.5至2.9;39人)。同一年龄段受试者中,确诊和疑似青光眼的患病率为3.1%(95%CI:2.4至4.0;58人)。原发性开角型青光眼是最常见的青光眼类型,占总数的75%。在非屈光不正导致的失明病例中,5%由青光眼引起。青光眼患病率男性高于女性,但未呈现典型的随年龄增长而增加的趋势。
孟加拉国青光眼患病率相对较高,尽管在社区失明病例中仅占一小部分。据估计,孟加拉国40岁及以上确诊或疑似青光眼的人数约为58.6万。