Wirtz Markus, Droux Michel
Heidelberg Institute of Plant Sciences (HIP), University of Heidelberg, Im Neuenheimer Feld 360, 69120 Heidelberg, Germany.
Photosynth Res. 2005 Dec;86(3):345-62. doi: 10.1007/s11120-005-8810-9. Epub 2005 Nov 12.
This review will assess new features reported for the molecular and biochemical aspects of cysteine and methionine biosynthesis in Arabidopsis thaliana with regards to early published data from other taxa including crop plants and bacteria (Escherichia coli as a model). By contrast to bacteria and fungi, plant cells present a complex organization, in which the sulfur network takes place in multiple sites. Particularly, the impact of sulfur amino-acid biosynthesis compartmentalization will be addressed in respect to localization of sulfur reduction. To this end, the review will focus on regulation of sulfate reduction by synthesis of cysteine through the cysteine synthase complex and the synthesis of methionine and its derivatives. Finally, regulatory aspects of sulfur amino-acid biosynthesis will be explored with regards to interlacing processes such as photosynthesis, carbon and nitrogen assimilation.
本综述将根据包括农作物和细菌（以大肠杆菌为模型）在内的其他分类群早期发表的数据，评估拟南芥中半胱氨酸和蛋氨酸生物合成的分子和生化方面的新特征。与细菌和真菌不同，植物细胞具有复杂的组织结构，其中硫代谢网络在多个位点进行。特别是，将针对硫还原的定位探讨硫氨基酸生物合成区室化的影响。为此，本综述将重点关注通过半胱氨酸合酶复合体合成半胱氨酸以及蛋氨酸及其衍生物的合成对硫酸盐还原的调节。最后，将探讨硫氨基酸生物合成的调控方面与光合作用、碳和氮同化等交织过程的关系。
