Zuo Yuegang, Zhang Kai, Deng Yiwei
Department of Chemistry and Biochemistry, University of Massachusetts Dartmouth and University of Massachusetts Graduate School of Marine Sciences and Technology, North Dartmouth, MA 02747, USA.
Chemosphere. 2006 Jun;63(9):1583-90. doi: 10.1016/j.chemosphere.2005.08.063. Epub 2005 Nov 22.
17alpha-Ethinylestradiol (EE2), a major constituent of common contraceptive pills, and three other estrogenic hormones, estrone (E1), 17beta-estradiol (E2) and mestranol (MeEE2) have been determined in Acushnet River Estuary seawater using a GC-MS technique. Among three estrogenic compounds detected, EE2 has the highest concentration, up to 4.7 ng/l, at which EE2 may affect lobster and other fish abundance in the coastal seawater due to its high biological activity on fish feminization. Two natural estrogenic hormones, E1 and E2 have also been found in the estuary at concentrations up to 1.2 ng/l and 0.83 ng/l, respectively. Although EE2 is persistent to microbial degradation, it can undergo a rapid photodegradation in estuarine seawater under natural sunlight irradiation, with a half-life of less than 1.5 days in spring sunny days.
利用气相色谱 - 质谱联用（GC-MS）技术，已测定了阿库什内特河河口海水中17α - 乙炔雌二醇（EE2）（常见避孕药的主要成分）以及其他三种雌激素——雌酮（E1）、17β - 雌二醇（E2）和炔雌醇甲醚（MeEE2）的含量。在所检测出的三种雌激素化合物中，EE2的浓度最高，可达4.7纳克/升，鉴于其对鱼类雌性化具有较高的生物活性，该浓度下的EE2可能会影响沿海海水中龙虾及其他鱼类的数量。在该河口还发现了两种天然雌激素E1和E2，其浓度分别高达1.2纳克/升和0.83纳克/升。尽管EE2对微生物降解具有抗性，但在自然阳光照射下，它在河口海水中可迅速发生光降解，在春季晴天时半衰期不到1.5天。
