起源走向塑料化。
Origins go plastic.
作者信息
Gilbert David M
机构信息
Department of Biochemistry and Molecular Biology, The State University of New York Upstate Medical University, 750 East Adams Street, Syracuse, New York 13210, USA.
出版信息
Mol Cell. 2005 Dec 9;20(5):657-8. doi: 10.1016/j.molcel.2005.11.013.
PMID:16337589
Abstract
Replication origins should no longer be thought of as housekeeping elements that function similarly in all cell types. provide the most authoritative evidence to date that mammalian replication origins can be dynamically regulated during differentiation.
摘要
复制起点不应再被视为在所有细胞类型中都以类似方式发挥作用的管家元件。提供了迄今为止最权威的证据，证明哺乳动物复制起点在分化过程中可被动态调控。
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