• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Oligomerization of G-protein-coupled receptors: lessons from the yeast Saccharomyces cerevisiae.

作者信息

Overton Mark C, Chinault Sharon L, Blumer Kendall J

机构信息

Department of Cell Biology and Physiology, Washington University School of Medicine, 660 S. Euclid Ave., St. Louis, MO 63110-1010, USA.

出版信息

Eukaryot Cell. 2005 Dec;4(12):1963-70. doi: 10.1128/EC.4.12.1963-1970.2005.

DOI:10.1128/EC.4.12.1963-1970.2005
PMID:16339714
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1317502/
Abstract
摘要

相似文献

1
Oligomerization of G-protein-coupled receptors: lessons from the yeast Saccharomyces cerevisiae.G蛋白偶联受体的寡聚化：来自酿酒酵母的启示。
Eukaryot Cell. 2005 Dec;4(12):1963-70. doi: 10.1128/EC.4.12.1963-1970.2005.
2
Subunits of a yeast oligomeric G protein-coupled receptor are activated independently by agonist but function in concert to activate G protein heterotrimers.酵母寡聚G蛋白偶联受体的亚基可被激动剂独立激活，但协同发挥作用以激活G蛋白异源三聚体。
J Biol Chem. 2004 Apr 16;279(16):16091-100. doi: 10.1074/jbc.M311099200. Epub 2004 Feb 5.
3
Oligomerization of the yeast alpha-factor receptor: implications for dominant negative effects of mutant receptors.酵母α因子受体的寡聚化：对突变受体显性负效应的影响。
J Biol Chem. 2006 Jul 28;281(30):20698-20714. doi: 10.1074/jbc.M513642200. Epub 2006 May 18.
4
G-protein-coupled receptor Gpr1 and G-protein Gpa2 of cAMP-dependent signaling pathway are involved in glucose-induced pexophagy in the yeast Saccharomyces cerevisiae.cAMP 依赖性信号通路的 G 蛋白偶联受体 Gpr1 和 G 蛋白 Gpa2 参与酿酒酵母中葡萄糖诱导的pexophagy。
Cell Biol Int. 2008 May;32(5):502-4. doi: 10.1016/j.cellbi.2007.11.001. Epub 2007 Nov 12.
5
Simultaneous method for analyzing dimerization and signaling of G-protein-coupled receptor in yeast by dual-color reporter system.利用双色报告系统分析酵母 G 蛋白偶联受体二聚化和信号转导的同时方法。
Biotechnol Bioeng. 2014 Mar;111(3):586-96. doi: 10.1002/bit.25125.
6
Focus Issue: New insights in GPCR to G protein signaling.专刊主题：G 蛋白偶联受体（GPCR）到 G 蛋白信号转导的新见解。
Sci Signal. 2016 Apr 12;9(423):eg6. doi: 10.1126/scisignal.aaf7642.
7
G-protein coupled receptor from yeast Saccharomyces cerevisiae.来自酿酒酵母的G蛋白偶联受体。
Biochem Biophys Res Commun. 1997 Nov 17;240(2):287-92. doi: 10.1006/bbrc.1997.7649.
8
Oligomerization, biogenesis, and signaling is promoted by a glycophorin A-like dimerization motif in transmembrane domain 1 of a yeast G protein-coupled receptor.酵母G蛋白偶联受体跨膜结构域1中类血型糖蛋白A二聚化基序可促进寡聚化、生物合成及信号传导。
J Biol Chem. 2003 Dec 5;278(49):49369-77. doi: 10.1074/jbc.M308654200. Epub 2003 Sep 23.
9
Protein–protein interactions and selection: yeast-based approaches that exploit guanine nucleotide-binding protein signaling.蛋白质-蛋白质相互作用和选择：基于酵母的方法，利用鸟嘌呤核苷酸结合蛋白信号转导。
FEBS J. 2010 May;277(9):1982-95. doi: 10.1111/j.1742-4658.2010.07625.x.
10
Dynamic roles for the N-terminus of the yeast G protein-coupled receptor Ste2p.酵母 G 蛋白偶联受体 Ste2p N 端的动态作用。
Biochim Biophys Acta Biomembr. 2017 Oct;1859(10):2058-2067. doi: 10.1016/j.bbamem.2017.07.014. Epub 2017 Jul 25.

引用本文的文献

1
Allosteric Regulation of G-Protein-Coupled Receptors: From Diversity of Molecular Mechanisms to Multiple Allosteric Sites and Their Ligands.别构调节 G 蛋白偶联受体：从分子机制多样性到多个别构结合位点及其配体。
Int J Mol Sci. 2023 Mar 24;24(7):6187. doi: 10.3390/ijms24076187.
2
Dielectric Spectroscopy Based Detection of Specific and Nonspecific Cellular Mechanisms.基于介电谱的特异性和非特异性细胞机制检测。
Sensors (Basel). 2021 May 3;21(9):3177. doi: 10.3390/s21093177.
3
The Ancient Link between G-Protein-Coupled Receptors and C-Terminal Phospholipid Kinase Domains.G 蛋白偶联受体与 C 端磷脂酶激酶结构域的古老联系。
mBio. 2018 Jan 23;9(1):e02119-17. doi: 10.1128/mBio.02119-17.
4
Push-Pull and Feedback Mechanisms Can Align Signaling System Outputs with Inputs.推拉和反馈机制可以使信号系统的输出与输入相匹配。
Cell Syst. 2016 Nov 23;3(5):444-455.e2. doi: 10.1016/j.cels.2016.10.002. Epub 2016 Oct 27.
5
Less is more: Nutrient limitation induces cross-talk of nutrient sensing pathways with NAD homeostasis and contributes to longevity.少即是多：营养限制诱导营养感应途径与NAD稳态之间的相互作用，并有助于延长寿命。
Front Biol (Beijing). 2015 Aug;10(4):333-357. doi: 10.1007/s11515-015-1367-x. Epub 2015 Jul 30.
6
Heterotrimeric G Protein-coupled Receptor Signaling in Yeast Mating Pheromone Response.酵母交配信息素应答中的异源三聚体G蛋白偶联受体信号传导
J Biol Chem. 2016 Apr 8;291(15):7788-95. doi: 10.1074/jbc.R116.714980. Epub 2016 Feb 23.
7
The transmembrane domain of CEACAM1-4S is a determinant of anchorage independent growth and tumorigenicity.CEACAM1-4S 的跨膜结构域是决定其锚定非依赖性生长和致瘤性的因素。
PLoS One. 2012;7(1):e29606. doi: 10.1371/journal.pone.0029606. Epub 2012 Jan 3.
8
In vivo quantification of G protein coupled receptor interactions using spectrally resolved two-photon microscopy.利用光谱分辨双光子显微镜对G蛋白偶联受体相互作用进行体内定量分析。
J Vis Exp. 2011 Jan 19(47):2247. doi: 10.3791/2247.
9
Modulation of HDL metabolism by the niacin receptor GPR109A in mouse hepatocytes.载脂蛋白代谢的调节在小鼠肝细胞中的烟酸受体 GPR109A。
Biochem Pharmacol. 2010 Nov 1;80(9):1450-7. doi: 10.1016/j.bcp.2010.07.023. Epub 2010 Jul 22.
10
Identification of the amino acid sequence that targets peroxiredoxin 6 to lysosome-like structures of lung epithelial cells.确定将过氧化物酶体增殖物激活受体6靶向肺上皮细胞溶酶体样结构的氨基酸序列。
Am J Physiol Lung Cell Mol Physiol. 2009 Nov;297(5):L871-80. doi: 10.1152/ajplung.00052.2009. Epub 2009 Aug 21.

本文引用的文献

1
Galpha subunit Gpa2 recruits kelch repeat subunits that inhibit receptor-G protein coupling during cAMP-induced dimorphic transitions in Saccharomyces cerevisiae.Gα亚基Gpa2募集kelch重复亚基，在酿酒酵母中cAMP诱导的二态转变过程中抑制受体-G蛋白偶联。
Mol Biol Cell. 2005 Oct;16(10):4557-71. doi: 10.1091/mbc.e05-05-0403. Epub 2005 Jul 19.
2
The specificity and molecular basis of alpha1-adrenoceptor and CXCR chemokine receptor dimerization.α1肾上腺素能受体与CXCR趋化因子受体二聚化的特异性及分子基础。
J Mol Neurosci. 2005;26(2-3):161-8. doi: 10.1385/JMN:26:2-3:161.
3
Monomeric G-protein-coupled receptor as a functional unit.单体G蛋白偶联受体作为一个功能单位。
Biochemistry. 2005 Jul 12;44(27):9395-403. doi: 10.1021/bi050720o.
4
Oligomerization of the fifth transmembrane domain from the adenosine A2A receptor.腺苷A2A受体第五跨膜结构域的寡聚化
Protein Sci. 2005 Aug;14(8):2177-86. doi: 10.1110/ps.051409205. Epub 2005 Jun 29.
5
Dimerization of chemokine receptors and its functional consequences.趋化因子受体的二聚化及其功能后果。
Cytokine Growth Factor Rev. 2005 Dec;16(6):611-23. doi: 10.1016/j.cytogfr.2005.05.005. Epub 2005 Jun 23.
6
Comparison of class A and D G protein-coupled receptors: common features in structure and activation.A类和D类G蛋白偶联受体的比较：结构与激活的共同特征
Biochemistry. 2005 Jun 28;44(25):8959-75. doi: 10.1021/bi047316u.
7
Diversifying the repertoire of G protein-coupled receptors through oligomerization.通过寡聚化使G蛋白偶联受体的受体库多样化。
Proc Natl Acad Sci U S A. 2005 Jun 21;102(25):8793-4. doi: 10.1073/pnas.0504016102. Epub 2005 Jun 13.
8
The genome of the social amoeba Dictyostelium discoideum.社会性变形虫盘基网柄菌的基因组。
Nature. 2005 May 5;435(7038):43-57. doi: 10.1038/nature03481.
9
Transduction of receptor signals by beta-arrestins.β-抑制蛋白介导的受体信号转导
Science. 2005 Apr 22;308(5721):512-7. doi: 10.1126/science.1109237.
10
Except in every detail: comparing and contrasting G-protein signaling in Saccharomyces cerevisiae and Schizosaccharomyces pombe.除了在每一个细节上：比较和对比酿酒酵母和粟酒裂殖酵母中的G蛋白信号传导。
Eukaryot Cell. 2005 Mar;4(3):495-503. doi: 10.1128/EC.4.3.495-503.2005.