用固载在多孔玻璃表面上的季铵盐对水进行消毒。
Disinfection of water with quaternary ammonium salts insolubilized on a porous glass surface.
机构信息
Department of Fermentation Technology, Faculty of Engineering, Osaka University, 2-1 Yamadaoka, Suita-shi, Osaka 565, and Department of Applied Chemistry, Technical College of Tokushima University, Tokushima 770, Japan.
出版信息
Appl Environ Microbiol. 1984 Mar;47(3):513-8. doi: 10.1128/aem.47.3.513-518.1984.
Insoluble quaternary ammonium salts bound to porous glass showed antibacterial activity. An agent designated as G(12), which had a dodecyl alkyl chain, was selected for some antibacterial tests on comparison of it with the agent reported previously. The antibacterial activity of G(12) toward Escherichia coli was mainly due to the adsorption of cells and therefore gradually decreased during continuous treatment of a cell suspension. The lost G(12) activity was completely recovered by washing with ethanol, and the activity of refreshed G(12) decreased in the same manner as that of fresh G(12). The lost activity was, however, always recovered only by ethanol treatment. This indicated that G(12) might interact with cells more strongly by means of a hydrophobic force than an electrostatic one. The antimicrobial spectrum showed that G(12) was effective against not only bacteria but also yeasts.
不溶性季铵盐与多孔玻璃结合表现出抗菌活性。选择了一种名为 G(12) 的试剂，它具有十二烷基链，与之前报道的试剂进行了一些抗菌测试比较。G(12)对大肠杆菌的抗菌活性主要归因于细胞的吸附，因此在连续处理细胞悬浮液时逐渐降低。用乙醇洗涤可完全回收失去的 G(12)活性，而用新鲜乙醇处理后的 G(12)的活性以相同的方式降低。然而，只有乙醇处理才能恢复失去的活性。这表明 G(12)可能通过疏水力而不是静电力与细胞更强地相互作用。抗菌谱表明，G(12)不仅对细菌有效，而且对酵母也有效。
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