Roessner V, Becker A, Banaschewski T, Rothenberger A
Department of Child and Adolescent Psychiatry, University of Göttingen, Germany.
J Neural Transm Suppl. 2005(69):69-99. doi: 10.1007/3-211-31222-6_5.
Over the last years evidence on the overlap between tic-disorders (TD) and obsessive compulsive behavior/disorder (OCB/OCD) has increased. The main focus of research have been the phenomenological and epidemiological similarities and differences in samples of different age, primary diagnosis (TD vs. OCD) including the co-occurrence of both. Unfortunately, only a minority of studies included all three groups (TD, TD + OCD, OCD). Nevertheless, new insight concerning possible subtypes for both TD and OCD has been gained. While some authors concentrated on OCD with/without tics we will summarize the field of TD and OCB/OCD from the viewpoint of tics, since OCB plays an important role in patients with TD. Thereby we will not only sharpen the clinicans' awareness of known differences in phenomenology, epidemiology, genetics and neurobiology, aimed to improve their diagnoses and treatment but also highlight the gaps of knowledge and discuss possibilities for further research in this field.
在过去几年中，抽动障碍（TD）与强迫行为/障碍（OCB/OCD）之间重叠的证据有所增加。研究的主要重点一直是不同年龄样本、主要诊断（TD与OCD）中的现象学和流行病学异同，包括两者的共病情况。不幸的是，只有少数研究纳入了所有三组（TD、TD+OCD、OCD）。然而，关于TD和OCD可能的亚型已经有了新的见解。虽然一些作者专注于伴有/不伴有抽动的OCD，但我们将从抽动的角度总结TD和OCB/OCD领域，因为OCB在TD患者中起着重要作用。借此，我们不仅将提高临床医生对现象学、流行病学、遗传学和神经生物学方面已知差异的认识，旨在改善他们的诊断和治疗，还将突出知识空白，并讨论该领域进一步研究的可能性。
