Dong Liang, Wang Jian-an, Jiang Chen-yang
Department of Cardiology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China.
J Zhejiang Univ Sci B. 2005 Dec;6(12):1157-62. doi: 10.1631/jzus.2005.B1157.
To compare a new device (Innocor) for non-invasive measurement of cardiac output (CO) by foreign gas rebreathing method with conventional techniques used in the measurements of cardiac function.
Cardiac outputs measured by Innocor (CO(RB)) were compared with CO obtained by echocardiography (CO(EC)), Swan-Ganz thermodilution (CO(TD)), and left ventricle radiography (CO(LVR)) in 34 patients subjected to cardiac catheterization. Values obtained from the four methods were analyzed by linear regression and paired values were compared by the method of Bland and Altman in SPSS.
There was strong positive correlation (r=0.94) between Innocor cardiac output values and the corresponding values obtained by thermodilution and between CO(EC) and CO(LVR) values. Thermodilution appears to overestimate cardiac output when compared to the values obtained with Innocor by (0.66+/-0.22) L/min (P<0.0001). There was no correlation between data obtained by Innocor and the corresponding CO(EC) and CO(LVR) values.
Innocor CO(RB) is an easy, safe and well established method for non-invasive measurement of cardiac output with good prospects for clinical application in heart disease patients.
采用外源性气体重呼吸法，使用一种新型设备（Innocor）无创测量心输出量（CO），并与测量心功能的传统技术进行比较。
在34例接受心导管检查的患者中，将Innocor测量的心输出量（CO(RB)）与经超声心动图（CO(EC)）、Swan-Ganz热稀释法（CO(TD)）和左心室造影术（CO(LVR)）获得的心输出量进行比较。采用线性回归分析这四种方法获得的值，并在SPSS中使用Bland和Altman方法比较配对值。
Innocor心输出量值与热稀释法获得的相应值之间以及CO(EC)和CO(LVR)值之间存在强正相关（r = 0.94）。与Innocor获得的值相比，热稀释法似乎高估了心输出量，差值为（0.66±0.22）L/min（P < 0.0001）。Innocor获得的数据与相应的CO(EC)和CO(LVR)值之间无相关性。
Innocor CO(RB)是一种简便、安全且成熟的无创测量心输出量的方法，在心脏病患者中具有良好的临床应用前景。
