Vestergaard Mogens, Obel Carsten, Henriksen Tine Brink, Christensen Jakob, Madsen Kreesten Meldgaard, Ostergaard John R, Olsen Jørn
The Danish Epidemiology Science Center at the Department of Epidemiology and Social Medicine, University of Aarhus, Vennelyst Boulevard 6, DK-8000 Aarhus C, Denmark.
J Clin Epidemiol. 2006 Jan;59(1):61-6. doi: 10.1016/j.jclinepi.2005.05.008. Epub 2005 Nov 2.
We examined the quality and completeness of the discharge diagnosis of febrile seizures in the Danish National Hospital Register (DNHR).
We invited all children born at the Department of Obstetrics, Aarhus University Hospital, Denmark, between January 1990 and April 1992, to participate in the study. We collected information on febrile seizures in March 2001 by mailing a questionnaire to the mothers. Reported febrile seizures were verified by telephone interviews or review of medical records. We linked the cohort to the DNHR by means of a unique civil registry number assigned to all Danish citizens at birth. Overall, 6,624 (73%) children participated in the study.
We found that 323 (4.9%) children in the cohort had had febrile seizures, and 231 of those were registered in the DNHR (completeness: 71.5%, 95% CI: 66.3-76.4). Furthermore, we confirmed the diagnosis in 231 of 249 children registered with febrile seizures in the DNHR (predictive value of a positive registration: 92.8%, 95% CI: 88.8-95.7).
The Danish National Hospital Register is a valuable tool for epidemiologic research in febrile seizures.
我们研究了丹麦国家医院登记册（DNHR）中热性惊厥出院诊断的质量和完整性。
我们邀请了1990年1月至1992年4月在丹麦奥胡斯大学医院妇产科出生的所有儿童参与该研究。2001年3月，我们通过向母亲邮寄问卷收集热性惊厥的信息。报告的热性惊厥通过电话访谈或病历审查进行核实。我们通过为所有丹麦公民出生时分配的唯一民事登记号码将该队列与DNHR相链接。总体而言，6624名（73%）儿童参与了该研究。
我们发现该队列中有323名（4.9%）儿童曾发生过热性惊厥，其中231名在DNHR中登记（完整性：71.5%，95%可信区间：66.3 - 76.4）。此外，我们在DNHR中登记的249名热性惊厥儿童中确认了231名的诊断（阳性登记的预测价值：92.8%，95%可信区间：88.8 - 95.7）。
丹麦国家医院登记册是热性惊厥流行病学研究的宝贵工具。
