Mukherjee Pratik
Neuroradiology Section, Department of Radiology, University of California at San Francisco, CA 94143-0628, USA.
Neuroimaging Clin N Am. 2005 Aug;15(3):655-65, xii. doi: 10.1016/j.nic.2005.08.010.
Diffusion tensor imaging (DTI) permits the quantitative evaluation of white matter pathology using measures of diffusion anisotropy. Fiber tractography based on DTI can reveal the three-dimensional white matter connectivity of the human brain. DTI fiber tractography is used to localize stroke lesions in relation to functionally important pathways and to assess wallerian degeneration, which may allow more accurate prognosis of long-term recovery or disability. DTI also improves the evaluation of hypoxic-ischemic injury to the developing brain of newborns and infants. DTI and fiber tractography may prove useful in elucidating alterations in brain connectivity resulting from neuroplasticity after stroke.
扩散张量成像(DTI)可通过扩散各向异性测量对白质病变进行定量评估。基于DTI的纤维束成像能够揭示人脑的三维白质连接情况。DTI纤维束成像用于确定中风病变与功能重要通路的关系,并评估华勒氏变性,这可能有助于更准确地预测长期恢复或残疾情况。DTI还能改善对新生儿和婴儿发育中大脑缺氧缺血性损伤的评估。DTI和纤维束成像可能在阐明中风后神经可塑性导致的脑连接改变方面发挥作用。