Handschel J G K, Depprich R A, Dirksen D, Runte C, Zimmermann A, Kübler N R
Department of Cranio- and Maxillofacial Surgery, Heinrich-Heine-University, Moorenstr. 5, D-40225 Düsseldorf, Germany.
Int J Oral Maxillofac Surg. 2006 Apr;35(4):318-23. doi: 10.1016/j.ijom.2005.10.003. Epub 2005 Dec 20.
Regarding the cosmetic results of wound closure using tissue adhesives as opposed to sutured wounds, most published studies are performed on children and with non-standardized lacerations, which makes it difficult to transfer the results to facial incisional wounds in adults. There are also conflicting conclusions about the cosmetic results. The purpose of this randomized prospective study was to compare the cosmetic outcomes of wound closure with sutures and octyl-2-cyanoacrylate in standardized facial wounds in adults. To compare very similar facial wounds, the infraorbital cut (lower eyelid incision) was used in 45 patients. The assessment was performed by patients and surgeons blind to the data. Phase-shifting profilometry was used to measure the profile of the scars. No early complications were observed in any group. The wound depth in the tissue adhesive group was significantly greater than in the suture group. There were no differences in the overall cosmetic results among all patients in the two groups. Interestingly, in the younger patients the result of the sutured wounds was superior to that of the adhesive-treated patients. The Dermabond skin adhesive provides a means of closure of facial surgical wounds without early complications, but adjustment of the edges of the wound and the cosmetic result in younger patients are less successful than with thin sutures.
关于使用组织粘合剂闭合伤口与缝合伤口的美容效果，大多数已发表的研究是在儿童身上进行的，且伤口为非标准化撕裂伤，这使得将结果应用于成人面部切口伤口变得困难。关于美容效果也存在相互矛盾的结论。这项随机前瞻性研究的目的是比较在成人标准化面部伤口中使用缝线和2-氰基丙烯酸辛酯闭合伤口的美容效果。为了比较非常相似的面部伤口，45例患者采用了眶下切口（下眼睑切口）。评估由对数据不知情的患者和外科医生进行。使用相移轮廓术测量疤痕轮廓。两组均未观察到早期并发症。组织粘合剂组的伤口深度明显大于缝线组。两组所有患者的总体美容效果没有差异。有趣的是，在年轻患者中，缝合伤口的效果优于粘合剂治疗的患者。皮肤粘合剂Dermabond提供了一种闭合面部手术伤口的方法，且无早期并发症，但在年轻患者中，伤口边缘的调整和美容效果不如细缝线。
