Nye Jonathon A, Avila-Rodriguez Miguel A, Nickles Robert J
Department of Medical Physics, University of Wisconsin Medical School, 1530 MSC, 1300 University Avenue Madison, Wisconsin 53706, USA.
Appl Radiat Isot. 2006 May;64(5):536-9. doi: 10.1016/j.apradiso.2005.11.010. Epub 2005 Dec 20.
A small-volume grid-supported niobium target was constructed for the production of [18F]-fluoride on a CTI RDS 112 cyclotron. The inert properties of niobium metal have proven compatible with the superheated environment generated during proton irradiation. A grid support, constructed from aluminum, provides the necessary heat removal for high-power irradiations. The niobium and gird combination supplies reactive fluoride over an extended target lifetime.