Bamberger David M, Boyd Sarah E
University of Missouri-Kansas City, School of Medicine, Kansas City, Missouri, USA.
Am Fam Physician. 2005 Dec 15;72(12):2474-81.
Because of high incidence, morbidity, and antimicrobial resistance, Staphylococcus aureus infections are a growing concern for family physicians. Strains of S. aureus that are resistant to vancomycin are now recognized. Increasing incidence of unrecognized community-acquired methicillin-resistant S. aureus infections pose a high risk for morbidity and mortality. Although the incidence of complex S. aureus infections is rising, new antimicrobial agents, including daptomycin and linezolid, are available as treatment. S. aureus is a common pathogen in skin, soft-tissue, catheter-related, bone, joint, pulmonary, and central nervous system infections. S. aureus bacteremias are particularly problematic because of the high incidence of associated complicated infections, including infective endocarditis. Adherence to precautions recommended by the Centers for Disease Control and Prevention, especially handwashing, is suboptimal.
由于金黄色葡萄球菌感染的高发病率、高患病率以及抗菌药物耐药性，其感染问题日益受到家庭医生的关注。现已发现对万古霉素耐药的金黄色葡萄球菌菌株。未被识别的社区获得性耐甲氧西林金黄色葡萄球菌感染发病率不断上升，导致发病和死亡风险增高。尽管复杂性金黄色葡萄球菌感染的发病率在上升，但包括达托霉素和利奈唑胺在内的新型抗菌药物可用于治疗。金黄色葡萄球菌是皮肤、软组织、导管相关、骨骼、关节、肺部和中枢神经系统感染中的常见病原体。金黄色葡萄球菌菌血症尤其成问题，因为包括感染性心内膜炎在内的相关复杂感染发病率很高。对疾病控制与预防中心推荐的预防措施，尤其是洗手的依从性欠佳。
