Coughlin S S, Beauchamp T L
Department of Medicine, Georgetown University School of Medicine, Washington, DC 20007.
Epidemiology. 1992 Jul;3(4):343-7. doi: 10.1097/00001648-199207000-00009.
Ethical conflicts between moral principles and methodologic standards sometimes occur in epidemiologic research. When dilemmas are discerned, they may be analyzed using the ethical principles of beneficence, nonmaleficence, justice, and respect for the autonomy of persons. We argue that, in addition to scientific validity, the welfare and rights of research subjects should be taken into account in making decisions regarding all aspects of the design and conduct of epidemiologic studies, and that the commitment of epidemiologists to the advancement of scientific knowledge should not outweigh or override all other considerations.
在流行病学研究中，道德原则与方法学标准之间有时会出现伦理冲突。当识别出困境时，可以运用有益、无害、公正以及尊重个人自主性等伦理原则进行分析。我们认为，除了科学有效性之外，在做出关于流行病学研究设计和实施的各个方面的决策时，还应考虑研究对象的福利和权利，并且流行病学家对科学知识进步的承诺不应超过或凌驾于所有其他考虑因素之上。
