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膳食脂肪与健康:证据及预防策略:合理使用膳食脂肪可改善生活并预防疾病。

Dietary fat and health: the evidence and the politics of prevention: careful use of dietary fats can improve life and prevent disease.

作者信息

Lands William E M

机构信息

College Park MD 20740 USA.

出版信息

Ann N Y Acad Sci. 2005 Dec;1055:179-92. doi: 10.1196/annals.1323.028.

Abstract

Every year, more young people start the slow progressive injury that eventually becomes cardiovascular disease and death. It could be prevented with nutrition education, but medical efforts focus more on treatments for older people than on preventing primary causes of disease in young people. Two avoidable risks are prevented by simple dietary interventions: (1) Eat more omega-3 and less omega-6 fats, so tissues have less intense n-6 eicosanoid action, and (2) eat less food per meal to lower vascular postprandial oxidant stress. An empirical diet-tissue relationship was developed and put into an interactive personalized software program to aid informed food choices.

摘要

每年,越来越多的年轻人开始遭受缓慢进展性损伤,最终发展为心血管疾病并导致死亡。通过营养教育本可预防这种情况,但医疗工作更多地侧重于对老年人的治疗,而非预防年轻人疾病的主要病因。通过简单的饮食干预可预防两种可避免的风险:(1)多摄入ω-3脂肪酸,少摄入ω-6脂肪酸,这样组织中n-6类二十烷酸的作用就会减弱;(2)每餐少吃食物以降低血管餐后氧化应激。建立了一种经验性的饮食与组织关系,并将其纳入一个交互式个性化软件程序,以帮助做出明智的食物选择。

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