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[黑腹果蝇中的超不稳定系统:无眼位点突变分析]

[Superunstable systems in Drosophila melanogaster: analysis of mutations in the ocelliless locus].

作者信息

Georgiev P G, Elagin V A

出版信息

Genetika. 1990 Aug;26(8):1416-26.

PMID:2175279
Abstract

Six super-unstable mutations were obtained after crossing the M-cytotype strain of Drosophila melanogaster, where transpositions of the Stalker mobile element occur, with the pi 2 strain. One of these mutations appeared at the ocelliless locus. Detailed genetic analysis of this mutation and its numerous super-unstable derivatives was performed. Eleven allelic classes with different expression of the oc phenotype were isolated. The main features of super-instability at the ocelliless locus have been described and found to be common for all super-unstable systems obtained in our experiments. The role of the P element in the induction of super-instability is discussed.

摘要

将发生Stalker转座元件转座的黑腹果蝇M细胞型品系与pi 2品系杂交后,获得了6个超级不稳定突变。其中一个突变出现在无单眼基因座。对该突变及其众多超级不稳定衍生物进行了详细的遗传分析。分离出了11个具有不同oc表型表达的等位基因类。描述了无单眼基因座超级不稳定的主要特征,并发现这些特征在我们实验中获得的所有超级不稳定系统中都很常见。讨论了P元件在诱导超级不稳定中的作用。

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