Bui Quoc E, Bernard A, Azan F, Renard G, Chauvaud D
Service d'Ophtalmologie, Hôtel-Dieu, 1, place du parvis Notre Dame, 75181 Paris Cedex 04, France.
J Fr Ophtalmol. 2005 Nov;28(9):944-52. doi: 10.1016/s0181-5512(05)81119-2.
Silicone oil is used in the treatment of rhegmatogenous retinal detachment when there is a high risk of postoperative proliferative vitreoretinopathy (PVR). This type of internal tamponade can be responsible for serious side effects. Removal of silicone oil is necessary to ensure a long-lasting functional result. The purpose of this study was to evaluate the results of using a transient internal tamponade with silicone oil.
A retrospective review of cases of rhegmatogenous retinal detachment treated with internal tamponade with silicone oil for the first time in a 1-year period (January 2001 to December 2001) was conducted. We studied the type of retinal detachment, treatment before vitrectomy and silicone oil tamponade, indication for silicone oil tamponade, surgical steps and their results, causes of recurrent retinal detachment, and final visual acuity. Anatomical success was defined as a reattached retina after silicone oil removal.
Ninety-three patients were included. Anatomical success was achieved, after one or several procedures, in 71 patients (76.3%). The mean total number of surgical procedures was 2.6. After initial surgery, recurrence of retinal detachment after removal of silicone oil occurred in 17.0% of the cases. Recurrence of retinal detachment under silicone oil occurred in 45.1% of the cases; the cause of the recurrence was PVR in 97.6% of those patients. No serious complication of silicone oil tamponade occurred. The mean duration of the tamponade was 6.7 months. The best results were achieved among patients showing no recurrence with silicone oil: visual acuity above 4/200 in 84.6% of the patients, above 20/200 in 61.5% of the patients and above 80/200 in 20.5% of the patients. In case of recurrence with silicone oil treatment, visual acuity reached 4/200 in 70.4% of the patients and was above 20/200 in 25.9% of the patients.
The results of this study are equivalent to those of studies in which analysis was made after removal of silicone oil. Proliferative vitreoretinopathy remains the only risk factor of retinal detachment recurrence with silicone oil (p<0.01). The number of previous surgeries is not a risk factor for postoperative PVR. Retinectomy is a surgical procedure that seems to improve the results in cases of severe PVR.
当术后增生性玻璃体视网膜病变(PVR)风险较高时,硅油用于治疗孔源性视网膜脱离。这种类型的眼内填充可能会导致严重的副作用。取出硅油对于确保长期的功能结果是必要的。本研究的目的是评估使用硅油进行短暂眼内填充的结果。
对在1年期间(2001年1月至2001年12月)首次接受硅油眼内填充治疗的孔源性视网膜脱离病例进行回顾性研究。我们研究了视网膜脱离的类型、玻璃体切除术前和硅油填充的治疗情况、硅油填充的指征、手术步骤及其结果、视网膜脱离复发的原因以及最终视力。解剖学成功定义为取出硅油后视网膜复位。
纳入93例患者。经过一次或多次手术,71例患者(76.3%)实现了解剖学成功。手术总次数的平均值为2.6次。初次手术后,取出硅油后视网膜脱离复发的发生率为17.0%。硅油填充期间视网膜脱离复发的发生率为45.1%;这些患者中97.6%的复发原因是PVR。未发生硅油填充的严重并发症。填充的平均持续时间为6.7个月。在硅油未复发的患者中取得了最佳结果:84.6%的患者视力高于4/200,61.5%的患者视力高于20/200,20.5%的患者视力高于80/200。在硅油治疗复发的情况下,70.4%的患者视力达到4/200,25.9%的患者视力高于20/200。
本研究的结果与在取出硅油后进行分析的研究结果相当。增生性玻璃体视网膜病变仍然是硅油导致视网膜脱离复发的唯一危险因素(p<0.01)。既往手术次数不是术后PVR的危险因素。视网膜切除术似乎能改善严重PVR病例的结果。