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一项针对人类弥漫性轴索损伤的拟议耐受标准。

A proposed tolerance criterion for diffuse axonal injury in man.

作者信息

Margulies S S, Thibault L E

机构信息

Thoracic Diseases Research Unit, Mayo Clinic, Rochester, MN 55905.

出版信息

J Biomech. 1992 Aug;25(8):917-23. doi: 10.1016/0021-9290(92)90231-o.

DOI:10.1016/0021-9290(92)90231-o
PMID:1639835
Abstract

The head injury criterion (HIC) is currently the government-accepted head injury indicator. The HIC is not injury-specific, does not relate to injury severity, nor does it take into account variations in the brain mass or load direction. This report focuses on one type of inertial brain injury, diffuse axonal injury (DAI), and utilizes animal studies, physical model experiments, and analytical model simulations to determine the kinematics of DAI in the subhuman primate and to scale these results to man. A human injury tolerance for moderate to severe DAI, which includes the influences of rotational loads and brain mass, is proposed.

摘要

头部损伤标准(HIC)目前是政府认可的头部损伤指标。HIC并非特定于某种损伤,与损伤严重程度无关,也未考虑脑质量或负荷方向的变化。本报告聚焦于一种惯性脑损伤,即弥漫性轴索损伤(DAI),并利用动物研究、物理模型实验和分析模型模拟来确定非人灵长类动物中DAI的运动学,并将这些结果按比例推算至人类。本文提出了一个包括旋转负荷和脑质量影响在内的中重度DAI的人体损伤耐受性。

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