Lim Wei-Yen, Saw Seang-Mei, Singh Manoj K, Au Eong Kah-Guan
Ministry of Health, College of Medicine Building, Singapore.
Clin Exp Ophthalmol. 2005 Dec;33(6):598-603. doi: 10.1111/j.1442-9071.2005.01102.x.
Although technologies to correct myopia have progressed in recent years, it is not known how cost-effective such technologies are. In this paper, utility values of myopic medical students in Singapore were ascertained as a first step to deriving weights for quality adjustment in future cost-effectiveness studies of such technologies.
Students (n = 120) aged 18-22 years with myopia (spherical equivalent at least -0.5 D) from Singapore's sole medical school were recruited. Information on lifetime intention to undergo refractive surgery, contact lens use, proportion of waking time spent wearing corrective devices, and utility values using the time trade-off and standard gamble for death methods, were obtained.
The mean utility values for time trade-off and standard gamble were 0.97 (95% confidence interval 0.96-0.98, median 1.00) and 0.99 (95% confidence interval 0.98-0.99, median 1.00), respectively. Utility values were significantly higher among those who reported a probability of less than 50% that they would undergo refractive surgery within their lifetime, compared with those who reported a probability of 50% or more (means 0.98 vs. 0.95, P < 0.001).
Utility values in myopic medical students obtained in this study appear to be relatively high, compared with those obtained for other ophthalmic conditions.
尽管近年来矫正近视的技术有所进步，但尚不清楚这些技术的成本效益如何。本文确定了新加坡近视医学生的效用值，作为在未来此类技术的成本效益研究中得出质量调整权重的第一步。
招募了来自新加坡唯一医学院的18至22岁患有近视（等效球镜至少为-0.5D）的120名学生。获取了有关接受屈光手术的终生意愿、隐形眼镜使用情况、醒着时佩戴矫正器具的时间比例以及使用时间权衡法和标准博弈法计算的效用值等信息。
时间权衡法和标准博弈法的平均效用值分别为0.97（95%置信区间0.96 - 0.98，中位数1.00）和0.99（95%置信区间0.98 - 0.99，中位数1.00）。报告终生接受屈光手术概率低于50%的学生的效用值显著高于报告概率为50%或更高的学生（均值分别为0.98对0.95，P < 0.001）。
与其他眼科疾病的效用值相比，本研究中获得的近视医学生的效用值似乎相对较高。
