Saw S-M, Gazzard G, Au Eong K-G, Koh D
Department of Community, Occupational and Family Medicine, National University of Singapore, 16 Medical Drive, Singapore 117597, Republic of Singapore.
Br J Ophthalmol. 2003 Mar;87(3):341-5. doi: 10.1136/bjo.87.3.341.
To ascertain the utility values of myopic teenage students in Singapore.
Children (n=699) aged 15-18 years with myopia (spherical equivalent (SE) at least -0.5 dioptres (D)) in two high schools in Singapore were recruited. Information on time trade-off (years of life willing to sacrifice for treatment of myopia) and standard gamble for blindness (risk of blindness from therapy willing to sacrifice for treatment of myopia) utility values, demographic, and socioeconomic status data were obtained.
The time trade-off and standard gamble for blindness utility values were 0.93 (95% confidence interval (CI) 0.93 to 0.94) and 0.85 (95% CI 0.84 to 0.86), respectively. Children with presenting better eye logMAR visual acuity >0.3 had lower time trade-off utility values (mean 0.92 versus mean 0.94), after adjusting for race and sex. There were dose-response relations between standard gamble for blindness values and total family income, as well as both utility values and educational stream (all p values for trend <0.01), after controlling for the same factors.
The utility values in myopic students were higher for teenagers with better presenting visual acuity, children who wore spectacles or contact lenses, higher total family income, more "academic" schooling stream, and who were non-Muslims.
确定新加坡近视青少年学生的效用值。
招募了新加坡两所高中的699名15 - 18岁近视（等效球镜度（SE）至少为-0.5屈光度（D））儿童。获取了关于时间权衡（愿意为近视治疗牺牲的生命年数）和失明的标准博弈（愿意为近视治疗牺牲的治疗导致失明的风险）效用值、人口统计学和社会经济状况数据。
时间权衡和失明的标准博弈效用值分别为0.93（95%置信区间（CI）0.93至0.94）和0.85（95%CI 0.84至0.86）。在调整种族和性别后，最佳矫正眼logMAR视力>0.3的儿童时间权衡效用值较低（均值0.92对均值0.94）。在控制相同因素后，失明的标准博弈值与家庭总收入之间以及效用值与教育类别之间均存在剂量反应关系（所有趋势p值<0.01）。
对于最佳矫正视力较好、佩戴眼镜或隐形眼镜、家庭总收入较高、接受更“学术性”教育类别且为非穆斯林的青少年近视学生，其效用值更高。
