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肝母细胞瘤:肿瘤学综述。

Hepatoblastoma: an oncological review.

作者信息

Roebuck Derek J, Perilongo Giorgio

机构信息

Department of Radiology, Great Ormond Street Hospital, London, WC1N 3JH, UK.

出版信息

Pediatr Radiol. 2006 Mar;36(3):183-6. doi: 10.1007/s00247-005-0064-3. Epub 2006 Jan 11.

DOI:10.1007/s00247-005-0064-3
PMID:16404556
Abstract

The treatment of hepatoblastoma is an example of the great advances made in paediatric oncology over the past few decades. Formerly a disease with a dreadful prognosis, children now have a 5-year survival rate of over 70%. This has been achieved by advances in surgical techniques and the use of chemotherapy. In future, we hope to be able to improve survival for children with high-risk tumours, and decrease the morbidity associated with treatment in the others.

摘要

肝母细胞瘤的治疗是过去几十年来儿科肿瘤学取得巨大进展的一个例子。以前这种疾病预后很差,而现在儿童的5年生存率超过了70%。这是通过手术技术的进步和化疗的应用实现的。未来,我们希望能够提高高危肿瘤患儿的生存率,并降低其他患儿治疗相关的发病率。

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Hepatoblastoma: an oncological review.肝母细胞瘤:肿瘤学综述。
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2
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3
[Differentiated treatment protocols for high- and standard-risk hepatoblastoma--an interim report of the German Liver Tumor Study HB99].[高风险和标准风险肝母细胞瘤的差异化治疗方案——德国肝脏肿瘤研究HB99的中期报告]
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J Pediatr Hematol Oncol. 2019 Apr;41(3):e171-e173. doi: 10.1097/MPH.0000000000001171.
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Intensified platinum therapy is an ineffective strategy for improving outcome in pediatric patients with advanced hepatoblastoma.强化铂类疗法对于改善晚期肝母细胞瘤患儿的预后而言是一种无效的策略。
J Clin Oncol. 2006 Jun 20;24(18):2879-84. doi: 10.1200/JCO.2005.02.6013.
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本文引用的文献

1
Surgical treatment of hepatoblastoma in children.儿童肝母细胞瘤的外科治疗
Pediatr Radiol. 2006 Mar;36(3):187-91. doi: 10.1007/s00247-005-0067-0. Epub 2006 Jan 11.
2
The emerging family of hepatoblastoma tumours: from ontogenesis to oncogenesis.肝母细胞瘤肿瘤的新兴家族:从个体发生到肿瘤发生
Eur J Cancer. 2005 Jul;41(11):1503-14. doi: 10.1016/j.ejca.2005.02.035.
3
Multidisciplinary treatment in children with non-metastatic hepatoblastoma: treatment results at the National Cancer Institute, Cairo University.非转移性肝母细胞瘤患儿的多学科治疗:开罗大学国家癌症研究所的治疗结果
在肝癌细胞中,IL-34 可能通过自分泌和旁分泌机制促进肿瘤进展。
Cancer Med. 2022 Mar;11(6):1441-1453. doi: 10.1002/cam4.4537. Epub 2022 Feb 8.
4
and polymorphisms are not associated with hepatoblastoma susceptibility in Chinese children.并且在中国儿童中,多态性与肝母细胞瘤易感性无关。
Exp Hematol Oncol. 2019 May 9;8:11. doi: 10.1186/s40164-019-0135-z. eCollection 2019.
5
Efficacy of preoperative transcatheter arterial chemoembolization combined with systemic chemotherapy for treatment of unresectable hepatoblastoma in children.术前经导管动脉化疗栓塞联合全身化疗治疗儿童不可切除肝母细胞瘤的疗效
Jpn J Radiol. 2014 Sep;32(9):529-36. doi: 10.1007/s11604-014-0340-y. Epub 2014 Jun 13.
6
Rare childhood tumors in a Turkish pediatric oncology center.土耳其一家儿科肿瘤中心的罕见儿童肿瘤
Indian J Med Paediatr Oncol. 2013 Oct;34(4):264-9. doi: 10.4103/0971-5851.125241.
7
An effective approach for treating unresectable hepatoblastoma in infants and children: Pre-operative transcatheter arterial chemoembolization.一种治疗婴幼儿不可切除性肝母细胞瘤的有效方法:术前经导管动脉化疗栓塞术。
Oncol Lett. 2013 Sep;6(3):850-854. doi: 10.3892/ol.2013.1444. Epub 2013 Jul 3.
8
Predictors of survival and incidence of hepatoblastoma in the paediatric population.儿童人群中肝母细胞瘤的生存和发病预测因素。
HPB (Oxford). 2013 Oct;15(10):741-6. doi: 10.1111/hpb.12112. Epub 2013 Apr 22.
9
Effect of duplex drugs linking 2'-deoxy-5-fluorouridine (5-FdU) with 3'-C-ethynylcytidine (ECyd) on hepatoblastoma cell lines.将2'-脱氧-5-氟尿苷(5-FdU)与3'-C-乙炔基胞苷(ECyd)连接的双联药物对肝母细胞瘤细胞系的影响。
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Pitfalls in paediatric oncology imaging.儿科肿瘤影像学中的陷阱。
Cancer Imaging. 2011 Sep 24;11(1):144-54. doi: 10.1102/1470-7330.2011.0021.
J Egypt Natl Canc Inst. 2004 Jun;16(2):92-8.
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The current management of hepatoblastoma: a combination of chemotherapy, conventional resection, and liver transplantation.肝母细胞瘤的当前治疗方法:化疗、传统切除术和肝移植的联合应用。
J Pediatr. 2005 Feb;146(2):204-11. doi: 10.1016/j.jpeds.2004.09.011.
5
Hepatoblastoma and hepatocellular carcinoma in children.儿童肝母细胞瘤和肝细胞癌
J Chin Med Assoc. 2004 Feb;67(2):83-8.
6
Risk-adapted treatment for childhood hepatoblastoma. final report of the second study of the International Society of Paediatric Oncology--SIOPEL 2.儿童肝母细胞瘤的风险适应性治疗。国际小儿肿瘤学会第二项研究——SIOPEL 2的最终报告。
Eur J Cancer. 2004 Feb;40(3):411-21. doi: 10.1016/j.ejca.2003.06.003.
7
[Differentiated treatment protocols for high- and standard-risk hepatoblastoma--an interim report of the German Liver Tumor Study HB99].[高风险和标准风险肝母细胞瘤的差异化治疗方案——德国肝脏肿瘤研究HB99的中期报告]
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Med Pediatr Oncol. 2002 Nov;39(5):510-8. doi: 10.1002/mpo.10177.
9
Treatment of unresectable and metastatic hepatoblastoma: a pediatric oncology group phase II study.不可切除和转移性肝母细胞瘤的治疗:一项儿科肿瘤学组II期研究
J Clin Oncol. 2002 Aug 15;20(16):3438-44. doi: 10.1200/JCO.2002.07.400.
10
Outcome of hepatoblastoma treated with the JPLT-1 (Japanese Study Group for Pediatric Liver Tumor) Protocol-1: A report from the Japanese Study Group for Pediatric Liver Tumor.采用JPLT-1(日本小儿肝脏肿瘤研究组)方案1治疗肝母细胞瘤的结果:来自日本小儿肝脏肿瘤研究组的报告。
J Pediatr Surg. 2002 Jun;37(6):851-6. doi: 10.1053/jpsu.2002.32886.