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研究方案——澳大利亚达尔文地区城市原住民中的糖尿病及相关病症:DRUID研究的目标、方法与参与情况

Study protocol--diabetes and related conditions in urban indigenous people in the Darwin, Australia region: aims, methods and participation in the DRUID Study.

作者信息

Cunningham Joan, O'Dea Kerin, Dunbar Terry, Weeramanthri Tarun, Zimmet Paul, Shaw Jonathan

机构信息

Menzies School of Health Research and Institute of Advances Studies, Charles Darwin University, PO Box 41096, Casuarina, NT 0811, Australia.

出版信息

BMC Public Health. 2006 Jan 17;6:8. doi: 10.1186/1471-2458-6-8.

Abstract

BACKGROUND

Diabetes mellitus is a serious and increasing health problem in Australia and is a designated national health priority. Diabetes and related conditions represent an even greater health burden among Indigenous Australians (Aborigines and Torres Strait Islanders), but there are critical gaps in knowledge relating to the incidence and prevalence, aetiology, and prevention of diabetes in this group, including a lack of information on the burden of disease among Indigenous people in urban areas. The DRUID Study (Diabetes and Related conditions in Urban Indigenous people in the Darwin region) was designed to address this knowledge gap.

METHODS/DESIGN: The study was conducted in a specified geographic area in and around Darwin, Australia. Eligible participants underwent a health examination, including collection of blood and urine samples, clinical and anthropometric measurements, and administration of questionnaires, with an additional assessment for people with diabetes. The study was designed to incorporate local Indigenous leadership, facilitate community engagement, and provide employment and training opportunities for local Indigenous people. A variety of recruitment methods were used. A total of 1,004 eligible people gave consent and provided at least one measurement. When compared with census data for the Indigenous population living in the study area, there was a marked under-representation of males, but no substantial differences in age, place of residence, Indigenous group, or household income. Early participants were more likely than later participants to have previously diagnosed diabetes.

DISCUSSION

Despite lower than anticipated recruitment, this is, to our knowledge, the largest study ever conducted on the health of Indigenous Australians living in urban areas, a group which comprises the majority of Australia's Indigenous population but about whose health and wellbeing relatively little is known. The study is well-placed to provide new information that can be used by policy makers and service providers to improve the delivery of services and programs that affect the health of Indigenous people. It also represents a valuable opportunity to establish an urban Indigenous cohort study, provided participants can be followed successfully over time.

摘要

背景

糖尿病在澳大利亚是一个严重且日益严峻的健康问题,是国家指定的健康重点问题。糖尿病及相关病症在澳大利亚原住民(澳大利亚土著居民和托雷斯海峡岛民)中构成了更沉重的健康负担,但在该群体中,关于糖尿病的发病率、患病率、病因及预防方面的知识存在重大空白,包括缺乏有关城市地区原住民疾病负担的信息。DRUID研究(达尔文地区城市原住民糖尿病及相关病症研究)旨在填补这一知识空白。

方法/设计:该研究在澳大利亚达尔文市及其周边的特定地理区域进行。符合条件的参与者接受了健康检查,包括采集血液和尿液样本、进行临床和人体测量以及发放问卷,对糖尿病患者还进行了额外评估。该研究旨在纳入当地原住民领导层,促进社区参与,并为当地原住民提供就业和培训机会。采用了多种招募方法。共有1004名符合条件的人同意参与并至少提供了一项测量数据。与研究区域内原住民人口的普查数据相比,男性的代表性明显不足,但在年龄、居住地点、原住民群体或家庭收入方面没有实质性差异。早期参与者比后期参与者更有可能之前已被诊断患有糖尿病。

讨论

尽管招募人数低于预期,但据我们所知,这是有史以来针对居住在城市地区的澳大利亚原住民健康状况开展的规模最大的研究,这一群体构成了澳大利亚原住民人口的大多数,但人们对其健康和福祉了解相对较少。该研究能够很好地提供新信息,供政策制定者和服务提供者用于改善影响原住民健康的服务和项目的提供。这也是建立城市原住民队列研究的宝贵机会,前提是能够随着时间的推移成功跟踪参与者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0925/1373687/c700d0fb60da/1471-2458-6-8-1.jpg

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