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英格兰少数族裔对肾脏替代疗法的需求情况。

The need and demand for renal replacement therapy in ethnic minorities in England.

作者信息

Roderick P J, Raleigh V S, Hallam L, Mallick N P

机构信息

Department of Public Health Medicine, University of Southampton.

出版信息

J Epidemiol Community Health. 1996 Jun;50(3):334-9. doi: 10.1136/jech.50.3.334.

Abstract

STUDY OBJECTIVE

The study aimed to determine the relative risk of being accepted for renal replacement treatment of black and Asian populations compared with whites in relation to age, sex, and underlying cause. The implications for population need for renal replacement therapy in these populations and for the development of renal services were also considered.

DESIGN/SETTING: This was a cross sectional retrospective survey of all patients accepted for renal replacement treatment in renal units in England in 1991 and 1992.

PATIENTS

These comprised all 5901 patients resident in England with end-stage renal failure who had been accepted for renal replacement therapy in renal units in England and whose ethnic category was available from the units. Patients were categorised as white, Asian, black, or other. Population denominators for the ethnic populations were taken from the 1991 census. The census categories Indian, Pakistani, and Bangladeshi were aggregated to form the denominator for Asian patients, and black Caribbeans, black Africans, and black others were aggregated to form the denominator for black patients.

MAIN RESULT

Altogether 7.7% of patients accepted were Asian and 4.7% were black; crude relative acceptance rates compared with whites were 3.5 and 3.2 respectively. Age sex specific relative acceptance ratios increased with age in both ethnic populations and were greater in females. Age standardised acceptance ratios were increased 4.2 and 3.7 times in Asian and black people respectively. The most common underlaying cause in both these populations was diabetes; relative rates of acceptance for diabetic end-stage renal failure were 5.8 and 6.5 respectively. The European Dialysis and Transplant Association coding system was inaccurate for disaggregating non-insulin and insulin dependent forms. "Unknown causes" were an important category in Asians with a relative acceptance of rate 5.7. The relative rates were reduced only slightly when the comparison was confined to the district health authorities with large ethnic minority populations, suggesting that geographical access was not a major factor in the high rates for ethnic minorities.

CONCLUSION

Acceptance rates for renal replacement treatment are increased significantly in Asian and black populations. Although data inaccuracies and access factors may contribute to these findings, the main reason is probably the higher incidence of end-stage renal failure. This in turn is due to the greater prevalence of underlying diseases such as non-insulin dependent diabetes but possibly also increased susceptibility of developing nethropathy. The main implication is that these populations age demand for renal replacement treatment will increase. This will have an impact nationally but will be particularly apparent in areas with large ethnic minority populations. Future planning must take these factors into account and should include strategies for preventing chronic renal failure, especially that due to non-insulin dependent diabetes and hypertension. The data could not determine the extent to which population need was being met; further studies are required to estimate the incidence of end-stage renal failure in ethnic minority populations.

摘要

研究目的

本研究旨在确定与白人相比,黑人和亚洲人群在年龄、性别及潜在病因方面接受肾脏替代治疗的相对风险。同时还考虑了这些人群对肾脏替代治疗的需求以及肾脏服务发展的影响。

设计/背景:这是一项对1991年和1992年在英格兰肾脏单位接受肾脏替代治疗的所有患者进行的横断面回顾性调查。

患者

这些患者包括居住在英格兰的所有5901例终末期肾衰竭患者,他们在英格兰的肾脏单位接受了肾脏替代治疗,且其种族类别可从各单位获取。患者被分为白人、亚洲人、黑人或其他种族。各民族人口的分母取自1991年人口普查数据。印度人、巴基斯坦人和孟加拉国人的普查类别合并后形成亚洲患者的分母,加勒比黑人、非洲黑人及其他黑人合并后形成黑人患者的分母。

主要结果

总共7.7%的接受治疗患者为亚洲人,4.7%为黑人;与白人相比,粗略的相对接受率分别为3.5和3.2。在这两个民族人群中,年龄和性别特异性相对接受率均随年龄增长而升高,女性的相对接受率更高。亚洲人和黑人的年龄标准化接受率分别提高了4.2倍和3.7倍。这两个人群中最常见的潜在病因是糖尿病;糖尿病终末期肾衰竭的相对接受率分别为5.8和6.5。欧洲透析和移植协会的编码系统在区分非胰岛素依赖型和胰岛素依赖型方面不准确。“不明原因”在亚洲人中是一个重要类别,相对接受率为5.7。当比较仅限于少数族裔人口较多的地区卫生当局时,相对比率仅略有降低,这表明地理可及性并非少数族裔接受率高的主要因素。

结论

亚洲人和黑人接受肾脏替代治疗的比率显著增加。尽管数据不准确和可及性因素可能导致这些结果,但主要原因可能是终末期肾衰竭的发病率较高。这反过来又归因于非胰岛素依赖型糖尿病等潜在疾病的患病率较高,但也可能是肾病易感性增加。主要影响是这些人群对肾脏替代治疗的需求将随着年龄增长而增加。这将在全国范围内产生影响,但在少数族裔人口较多的地区尤为明显。未来规划必须考虑这些因素,应包括预防慢性肾衰竭的策略,尤其是由非胰岛素依赖型糖尿病和高血压引起的慢性肾衰竭。这些数据无法确定人群需求得到满足的程度;需要进一步研究以估计少数族裔人群终末期肾衰竭的发病率。

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