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三大洲10年间收集的不动杆菌属中OXA-58样碳青霉烯酶的出现情况。

Occurrence of OXA-58-like carbapenemases in Acinetobacter spp. collected over 10 years in three continents.

作者信息

Coelho Juliana, Woodford Neil, Afzal-Shah Mariya, Livermore David

机构信息

Antibiotic Resistance Monitoring and Reference Laboratory, Health Protection Agency Centre for Infections, 61 Colindale Avenue, London NW9 5HT, United Kingdom.

出版信息

Antimicrob Agents Chemother. 2006 Feb;50(2):756-8. doi: 10.1128/AAC.50.2.756-758.2006.

DOI:10.1128/AAC.50.2.756-758.2006
PMID:16436738
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1366923/
Abstract

OXA-58 is a recently described carbapenemase from Acinetobacter spp. in Europe. We examined earlier worldwide Acinetobacter collections and found bla(OXA-58) in 30 carbapenem-nonsusceptible isolates, including several isolates collected in Argentina and Kuwait in 1995 and 1996 and in a British outbreak strain from 2000. Most isolates (28 of 30) also had bla(OXA-51). We conclude that bla(OXA-58) is geographically widespread and has occurred in Acinetobacter spp. for over 10 years.

摘要

OXA-58是欧洲最近报道的一种来自不动杆菌属的碳青霉烯酶。我们检查了此前全球范围内的不动杆菌菌株，在30株对碳青霉烯不敏感的分离株中发现了bla(OXA-58)，其中包括1995年和1996年在阿根廷和科威特收集的几株分离株以及2000年英国暴发菌株中的一株。大多数分离株（30株中的28株）也携带bla(OXA-51)。我们得出结论，bla(OXA-58)在地理上分布广泛，并且已经在不动杆菌属中存在超过10年。

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