Koçak Hikmet, Karapolat Sami, Gündogdu Cemal, Bozkurt Engin, Unlü Yahya
Department of Cardiovascular Surgery, Faculty of Medicine, Atatürk University, Erzurum, Turkey.
Heart Vessels. 2006 Jan;21(1):56-8. doi: 10.1007/s00380-005-0830-z.
Primary cardiac osteosarcomas are uncommon tumors. Their growth pattern is aggressive and the prognosis is poor. A 34-year-old, 7-month pregnant woman with a primary cardiac osteosarcoma associated with the anterior mitral leaflet and connected to the interatrial septum, causing nearly subtotal obstruction of the mitral valve, presented with a clinical picture of heart failure. Transthoracic echocardiography demonstrated an abnormal mass located in the mitral anterior leaflet, prolapsing into the left ventricle. Radical resection of the mass and replacement of the mitral valve were performed under cardiopulmonary bypass. Histopathology showed a low-grade osteosarcoma. The postoperative course was uneventful, and the patient was discharged on the 16th day after surgery. She gave birth after 2 months to a healthy baby after the successful operation. She and her baby did not have any problem during 3 months of follow-up.
原发性心脏骨肉瘤是罕见的肿瘤。它们的生长方式具有侵袭性,预后较差。一名34岁、怀孕7个月的女性患有原发性心脏骨肉瘤,该肿瘤与二尖瓣前叶相关并连接至房间隔,导致二尖瓣几乎完全梗阻,表现为心力衰竭的临床症状。经胸超声心动图显示二尖瓣前叶有一异常肿块,突入左心室。在体外循环下对肿块进行了根治性切除并置换了二尖瓣。组织病理学显示为低级别骨肉瘤。术后过程顺利,患者在手术后第16天出院。成功手术后2个月,她生下了一个健康的婴儿。在3个月的随访期间,她和她的宝宝没有任何问题。