Detaboada Luis, Ilic Sanja, Leichliter-Martha Sandra, Oron Uri, Oron Amir, Streeter Jackson
Photothera, Inc., 2260 Rutherford Road, Carlsbad, California 92008, USA.
Lasers Surg Med. 2006 Jan;38(1):70-3. doi: 10.1002/lsm.20256.
Low-level laser therapy (LLLT) has been shown to have beneficial effects on ischemic skeletal and heart muscles tissues. The aim of the present study was to approve the effectiveness of LLLT treatment at different locations on the brain in acute stroked rats.
STUDY DESIGN/MATERIALS AND METHODS: Stroke was induced in 169 rats that were divided into four groups: control non-laser and three laser-treated groups where laser was employed ipsilateral, contralateral, and both to the side of the induced stroke. Rats were tested for neurological function.
In all three laser-treated groups, a marked and significant improvement in neurological deficits was evident at 14, 21, and 28 days post stroke relative to the non-treated group.
These observations suggest that LLLT applied at different locations in the skull and in a rather delayed-phase post stroke effectively improves neurological function after acute stroke in rats.
低强度激光疗法（LLLT）已被证明对缺血性骨骼肌和心肌组织具有有益作用。本研究的目的是验证低强度激光疗法对急性中风大鼠大脑不同部位的治疗效果。
研究设计/材料与方法：对169只大鼠诱导中风，并将其分为四组：非激光治疗对照组和三个激光治疗组，激光分别照射在诱发中风一侧的同侧、对侧以及双侧。对大鼠的神经功能进行测试。
与未治疗组相比，在中风后14天、21天和28天，所有三个激光治疗组的神经功能缺损均有显著改善。
这些观察结果表明，在颅骨不同部位以及中风后相当延迟的阶段应用低强度激光疗法，可有效改善大鼠急性中风后的神经功能。
