Sharan Sapna, Sharma Shanel, Billson Frank A
Clin Exp Ophthalmol. 2006 Jan-Feb;34(1):83-4. doi: 10.1111/j.1442-9071.2006.01124.x.
Maternal infection with rubella in the first trimester is an important cause of congenital cataract. Any injury affecting the foetus following maternal rubella infection in the phase of organogenesis results in congenital defects collectively termed as congenital rubella syndrome (CRS). Although rubella embryopathy is a less common cause for congenital cataract than in the past, it is still seen. The number of cases reduced to one in 1997 after which there were no new cases till 2002. However, there have been two new cases of CRS in 2003. Herein another one in early 2004 is reported. Outbreaks of CRS will continue until the percentage of susceptible individuals is reduced to a minimum through immunization. The majority of rubella cases in Australia are confined to young female immigrants, many coming for marriage. We must continue to immunize children, identify and immunize vaccine failures and susceptible women before they become pregnant, and to screen pregnant women so they can be vaccinated after delivery.
孕期头三个月孕妇感染风疹是先天性白内障的一个重要病因。在器官形成期孕妇感染风疹后，任何影响胎儿的损伤都会导致先天性缺陷，这些缺陷统称为先天性风疹综合征（CRS）。尽管风疹胚胎病导致先天性白内障的情况比过去少见，但仍有发生。1997年病例数降至1例，此后到2002年没有新病例。然而，2003年出现了两例新的先天性风疹综合征病例。本文报告了2004年初的另一例病例。在通过免疫将易感人群比例降至最低之前，先天性风疹综合征的疫情将持续存在。澳大利亚的大多数风疹病例局限于年轻的女性移民，其中许多是来结婚的。我们必须继续为儿童接种疫苗，识别并为疫苗接种失败的人群以及易感女性在怀孕前接种疫苗，并对孕妇进行筛查，以便她们在分娩后能够接种疫苗。
