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有顺应性血管壁和无顺应性血管壁情况下全腔肺循环计算模拟中的效率差异。

Efficiency differences in computational simulations of the total cavo-pulmonary circulation with and without compliant vessel walls.

作者信息

Orlando Wendell, Shandas Robin, DeGroff Curt

机构信息

Northwest Research Associates, Inc., Colorado Research Associates Division, 3380 Mitchell Lane, Boulder, CO 80301, USA.

出版信息

Comput Methods Programs Biomed. 2006 Mar;81(3):220-7. doi: 10.1016/j.cmpb.2005.11.010. Epub 2006 Feb 7.

Abstract

The Fontan operation is a palliative surgical procedure performed on children born with congenital defects of the heart that have yielded only a single functioning ventricle. The total cavo-pulmonary connection (TCPC) is the most popular variant of the Fontan procedure. The objective of the study was to quantify and compare the efficiency of numerical models of the TCPC with rigid versus elastic vessel wall models. The pressure drop and power loss through both type TCPC models was measured. Significant differences in efficiencies exist between rigid versus elastic numerical models. We have shown incorporating elasticity into numerical models of the total cavo-pulmonary connection is important when determining circuit efficiencies.

摘要

Fontan手术是一种针对患有先天性心脏缺陷且仅有一个功能心室的儿童进行的姑息性外科手术。全腔静脉-肺动脉连接术(TCPC)是Fontan手术最常见的变体。本研究的目的是量化并比较刚性血管壁模型与弹性血管壁模型的TCPC数值模型的效率。测量了两种类型TCPC模型的压降和功率损失。刚性和弹性数值模型之间的效率存在显著差异。我们已经表明,在确定循环效率时,将弹性纳入全腔静脉-肺动脉连接的数值模型中很重要。

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