Cohen Seth, Dalle Frédéric, Gallay Anne, Di Palma Marc, Bonnin Alain, Ward Honorine D
Division of Geographic Medicine and Infectious Diseases, Tufts-New England Medical Center, Boston, MA 02111, USA.
J Clin Microbiol. 2006 Feb;44(2):589-91. doi: 10.1128/JCM.44.2.589-591.2006.
Cryptosporidium sp. isolates from a waterborne outbreak of diarrhea in France were analyzed by PCR-restriction fragment length polymorphism analysis and sequencing of the Cpgp40/15 locus. Ninety-one percent of the isolates were Cryptosporidium hominis type Ib. The results of this study and those of studies of other outbreaks suggest that the type Ib allele is the predominant allele associated with waterborne cryptosporidiosis.
通过聚合酶链反应-限制性片段长度多态性分析及Cpgp40/15基因座测序,对法国一起水源性腹泻暴发中分离出的隐孢子虫属菌株进行了分析。91%的分离菌株为微小隐孢子虫Ib型。本研究结果以及其他暴发研究结果表明,Ib型等位基因是与水源性隐孢子虫病相关的主要等位基因。