Muthusamy Dheepa, Rao Sitara S, Ramani Sasirekha, Monica Bindhu, Banerjee Indrani, Abraham Ooriapadickal C, Mathai Dilip C, Primrose Beryl, Muliyil Jayaprakash, Wanke Christine A, Ward Honorine D, Kang Gagandeep
Department of Gastrointestinal Sciences, Christian Medical College, Vellore, 632004, India.
J Clin Microbiol. 2006 Feb;44(2):632-4. doi: 10.1128/JCM.44.2.632-634.2006.
This study characterized cryptosporidial infections in 48 human immunodeficiency virus-infected individuals in India by multilocus genotyping. Cryptosporidium hominis, C. parvum, C. felis, C. muris, and C. meleagridis were identified. Cpgp40/15 PCR-restriction fragment length polymorphism identified six subgenotypes. Cryptosporidial diarrhea was associated with decreased CD4 counts, below 200 (P = 0.009), but not high viral loads.
本研究通过多位点基因分型对印度48名感染人类免疫缺陷病毒的个体中的隐孢子虫感染进行了特征分析。鉴定出了人隐孢子虫、微小隐孢子虫、猫隐孢子虫、鼠隐孢子虫和火鸡隐孢子虫。Cpgp40/15聚合酶链反应-限制性片段长度多态性鉴定出6种亚型。隐孢子虫性腹泻与CD4细胞计数降低有关,低于200个/μl(P = 0.009),但与高病毒载量无关。