• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Symptoms of extraesophageal reflux in a community-dwelling sample.

作者信息

Connor Nadine P, Palazzi-Churas Kerrin L P, Cohen Stacy B, Leverson Glen E, Bless Diane M

机构信息

Department of Communicative Disorders, University of Wisconsin-Madison, Madison, Wisconsin, USA.

出版信息

J Voice. 2007 Mar;21(2):189-202. doi: 10.1016/j.jvoice.2005.10.006. Epub 2006 Feb 10.

DOI:10.1016/j.jvoice.2005.10.006
PMID:16472972
Abstract

OBJECTIVES

Extraesophageal reflux disease (EERD) is linked with serious and varied health concerns. The authors' goal was to determine the prevalence of EERD and the effect on health-related quality of life in adults within a large community-based sample.

STUDY DESIGN

Survey study conducted in a community setting.

METHODS

In the Madison, Wisconsin area, 1845 adult subjects were surveyed. Main outcome measures were frequently of GERD and laryngeal symptoms, the Medical Outcomes Trust Short Form 12 (SF-12), Voice Handicap Index (VHI), and Quality of Life in Reflux and Dyspepsia (QOLRAD) questionnaires.

RESULTS

More than 66% of subjects reported either GERD or laryngeal symptoms, and 26% reported both GERD and laryngeal symptoms (which reflect symptoms commonly reported for EERD). In addition, 39% of our sample took medicine for heartburn. Forty-four percent of subjects with both GERD and laryngeal symptoms reported occasional breathing difficulties, and 38% of these subjects reported a voice disorder. Significant reductions in perceived quality of general health, digestive health, and voice-related quality of life were found in subjects with both GERD and laryngeal symptoms, in comparison with subjects manifesting each symptom group alone, or in subjects with no symptoms.

CONCLUSIONS

The presence of GERD and laryngeal symptoms, and their concurrence, was identified in a substantial number of subjects. The GERD and laryngeal symptoms surveyed represent those most commonly reported for EERD. Because EERD has been linked with tissue damage and reductions in health-related quality of life, it is important to identify these persons and provide treatment before progression of the condition.

摘要

相似文献

1
Symptoms of extraesophageal reflux in a community-dwelling sample.
J Voice. 2007 Mar;21(2):189-202. doi: 10.1016/j.jvoice.2005.10.006. Epub 2006 Feb 10.
2
Association of extraesophageal reflux disease and sinonasal symptoms: prevalence and impact on quality of life.食管外反流病与鼻-鼻窦症状的关联:患病率及对生活质量的影响。
Laryngoscope. 2007 Dec;117(12):2218-28. doi: 10.1097/MLG.0b013e31813e5fd7.
3
Quality of life in patients with laryngopharyngeal reflux.喉咽反流患者的生活质量
Digestion. 2009;79(1):52-7. doi: 10.1159/000205267. Epub 2008 Oct 22.
4
Impact of reflux disease on general and disease-related quality of life - evidence from a recent comparative methodological study in Germany.反流性疾病对总体生活质量和疾病相关生活质量的影响——来自德国近期一项比较方法学研究的证据。
Z Gastroenterol. 2003 Dec;41(12):1137-43. doi: 10.1055/s-2003-45277.
5
Concomitant functional dyspepsia and irritable bowel syndrome decrease health-related quality of life in gastroesophageal reflux disease.功能性消化不良和肠易激综合征并存会降低胃食管反流病患者的健康相关生活质量。
Scand J Gastroenterol. 2007 Aug;42(8):951-6. doi: 10.1080/00365520701204204.
6
Comparison of Pediatric Voice Outcome Survey, Reflux Symptom Index, Reflux Finding Score, and esophageal biopsy results.儿童嗓音结果调查问卷、反流症状指数、反流发现评分及食管活检结果的比较
Arch Otolaryngol Head Neck Surg. 2008 Aug;134(8):837-41. doi: 10.1001/archotol.134.8.837.
7
[Burden of illness in Polish patients with reflux disease].[波兰反流病患者的疾病负担]
Przegl Epidemiol. 2005;59(1):75-85.
8
Effects of gastroesophageal reflux disease on sleep and outcomes.胃食管反流病对睡眠及预后的影响。
Clin Gastroenterol Hepatol. 2009 Sep;7(9):953-9. doi: 10.1016/j.cgh.2009.04.005. Epub 2009 Apr 16.
9
Night-time and daytime atypical manifestations of gastro-oesophageal reflux disease: frequency, severity and impact on health-related quality of life.胃食管反流病的夜间和日间非典型表现:频率、严重程度及对健康相关生活质量的影响
Aliment Pharmacol Ther. 2008 Feb 15;27(4):327-37. doi: 10.1111/j.1365-2036.2007.03574.x. Epub 2007 Nov 13.
10
Prevalence of gastroesophageal reflux disease in patients with laryngeal and voice disorders.喉及嗓音障碍患者中胃食管反流病的患病率
Saudi Med J. 2007 Jul;28(7):1068-71.

引用本文的文献

1
The San Diego Consensus for Laryngopharyngeal Symptoms and Laryngopharyngeal Reflux Disease.《喉咽症状与喉咽反流病圣地亚哥共识》
Am J Gastroenterol. 2025 Apr 8. doi: 10.14309/ajg.0000000000003482.
2
Inhaled fosamprenavir for laryngopharyngeal reflux: Toxicology and fluid dynamics modeling.吸入式福沙那韦治疗喉咽反流:毒理学与流体动力学建模
Laryngoscope Investig Otolaryngol. 2024 Jan 24;9(1):e1219. doi: 10.1002/lio2.1219. eCollection 2024 Feb.
3
Association between oropharyngeal ph-monitoring, pepsin saliva concentration and degree of apnea-hypopnea index of obstructive sleep apnea.
口咽 ph 监测、胃蛋白酶唾液浓度与阻塞性睡眠呼吸暂停低通气指数严重程度的关系。
J Otolaryngol Head Neck Surg. 2023 Oct 14;52(1):68. doi: 10.1186/s40463-023-00675-0.
4
Predictors of Early and Late Response to Esomezol and Lifestyle Modification in Adults With Laryngopharyngeal Reflux Disease: A Prospective, Multicenter, Open-Label Cohort Study.成人喉咽反流病患者对埃索美拉唑和生活方式改变的早期及晚期反应的预测因素:一项前瞻性、多中心、开放标签队列研究。
Clin Exp Otorhinolaryngol. 2023 Aug;16(3):259-274. doi: 10.21053/ceo.2023.00409. Epub 2023 Jun 19.
5
To Determine the Prevalence of Laryngopharyngeal Reflux in Patients of Various Throat Disorders and to Evaluate the Efficacy of Anti-reflux Therapy.确定各种咽喉疾病患者中喉咽反流的患病率,并评估抗反流治疗的疗效。
Indian J Otolaryngol Head Neck Surg. 2023 Jun;75(2):720-724. doi: 10.1007/s12070-022-03273-0. Epub 2023 Jan 6.
6
Clinical Update Findings about pH-Impedance Monitoring Features in Laryngopharyngeal Reflux Patients.喉咽反流患者pH阻抗监测特征的临床最新研究结果
J Clin Med. 2022 Jun 1;11(11):3158. doi: 10.3390/jcm11113158.
7
How I Approach Laryngopharyngoesophageal Reflux (LPR).我如何处理喉咽食管反流(LPR)。
Curr Gastroenterol Rep. 2021 Nov 19;23(12):27. doi: 10.1007/s11894-021-00823-4.
8
[Current possibilities and challenges in the diagnosis of laryngopharyngeal reflux].[喉咽反流诊断的当前可能性与挑战]
HNO. 2021 Nov;69(11):861-867. doi: 10.1007/s00106-021-01006-3. Epub 2021 Feb 22.
9
Baseline impedance via manometry and ambulatory reflux testing are not equivalent when utilized in the evaluation of potential extra-esophageal gastroesophageal reflux disease.在评估潜在的食管外胃食管反流病时,通过测压法和动态反流测试得出的基线阻抗并不等同。
J Thorac Dis. 2020 Oct;12(10):5628-5638. doi: 10.21037/jtd-20-1623.
10
How to Approach Laryngopharyngeal Reflux: An Otolaryngology Perspective.如何应对喉咽反流:耳鼻咽喉科视角
Curr Gastroenterol Rep. 2016 Aug;18(8):44. doi: 10.1007/s11894-016-0515-z.