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癫痫发作与晕厥:解剖学基础及诊断要点

Seizures and syncope: anatomic basis and diagnostic considerations.

作者信息

Britton Jeffrey W, Benarroch Eduardo

机构信息

Sections of Epilepsy and Clinical Neurophysiology/EEG, Dept. of Neurology, West 8 Mayo Building, Mayo Clinic Rochester, 200 First Street SW, Rochester, MN 55905, USA.

出版信息

Clin Auton Res. 2006 Feb;16(1):18-28. doi: 10.1007/s10286-006-0277-z.

DOI:10.1007/s10286-006-0277-z
PMID:16477491
Abstract

Although pathophysiologically distinct, syncope and seizures share clinical characteristics which may make diagnosis difficult. Adding to diagnostic complexity are the facts that seizures and syncope may coexist in the same patient, syncope may be associated with seizure-like motor manifestations, and seizures may be complicated by cardiac arrhythmia and syncope. Combined EEG/ECG telemetry is sometimes necessary to establish the correct diagnosis. These techniques also provide an opportunity to study the role of certain cortical regions in the modulation of cardiac function. There is an increasing understanding of the central autonomic pathways involved in the genesis of the cardiovascular changes that occur during epileptic seizures. This article reviews the use of EEG/ECG telemetry in the evaluation of syncope and seizures, and the neuroanatomic circuitry involved in the production of the cardiovascular manifestations of seizures.

摘要

尽管晕厥和癫痫在病理生理上有所不同,但它们具有一些共同的临床特征,这可能会使诊断变得困难。癫痫和晕厥可能在同一患者中并存、晕厥可能与癫痫样运动表现相关以及癫痫可能并发心律失常和晕厥等情况,这进一步增加了诊断的复杂性。有时需要联合脑电图/心电图遥测来确立正确的诊断。这些技术还提供了一个机会来研究某些皮质区域在调节心脏功能中的作用。人们对癫痫发作期间发生的心血管变化的发生过程中涉及的中枢自主神经通路的认识越来越深入。本文综述了脑电图/心电图遥测在晕厥和癫痫评估中的应用,以及癫痫心血管表现产生过程中涉及的神经解剖学通路。

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Do antiepileptic drugs play a role in sudden unexpected death in epilepsy?抗癫痫药物在癫痫性猝死中起作用吗?
Drug Saf. 2003;26(10):673-83. doi: 10.2165/00002018-200326100-00001.
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Cardiac troponin levels following monitored epileptic seizures.监测癫痫发作后的心肌肌钙蛋白水平。
Neurology. 2003 May 27;60(10):1690-2. doi: 10.1212/01.wnl.0000065881.46964.4f.
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Differential diagnosis of cardiogenic syncope and seizure disorders.心源性晕厥与癫痫性疾病的鉴别诊断。
癫痫患者的突发性意外死亡:文献综述。
Epilepsia Open. 2023 Sep;8(3):728-757. doi: 10.1002/epi4.12722. Epub 2023 May 17.
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Bradycardia in a Woman Presenting with Altered Behaviour.一名行为改变女性的心动过缓
Acta Cardiol Sin. 2023 Jan;39(1):177-180. doi: 10.6515/ACS.202301_39(1).20220820A.
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Clinical Study of Autonomic Dysfunction in Patients With Anti-NMDA Receptor Encephalitis.抗N-甲基-D-天冬氨酸受体脑炎患者自主神经功能障碍的临床研究
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Anti-N-methyl-d-aspartate Receptor Encephalitis Related Sinus Node Dysfunction and the Lock-Step Phenomenon.抗N-甲基-D-天冬氨酸受体脑炎相关的窦房结功能障碍及同步现象
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