Elian Dan, Osherov Azriel, Matetzky Shlomi, Hod Hanoch, Guetta Victor, Feinberg Micha S, Di Segni Elio
Heart Institute, Sheba Medical Center, Tel-Hashomer, Israel.
Clin Cardiol. 2006 Jan;29(1):9-12. doi: 10.1002/clc.4960290104.
Left ventricular apical ballooning, a new syndrome recently described in Japan, is characterized by chest pain, electrocardiographic changes mimicking acute myocardial infarction, and transient apical dyskinesia with normal coronary arteries. Although several studies have defined the clinical characteristics, the prevalence of this syndrome remains unclear.
This study sought to determine the prevalence of left ventricular apical ballooning syndrome.
From January 2002 to September 2004, clinical, echocardiographic, and angiographic data of hospitalization and follow-up were collected from 638 consecutive patients referred to our Heart Institute for primary percutaneous intervention.
Thirteen patients (2%) were diagnosed with transient left ventricular apical ballooning. All but one patient were women, representing a 6% incidence for the female patients with acute myocardial infarction. A triggering factor was identified in eight. One patient died of cardiogenic shock. Left ventricular systolic function recovered completely within 4-5 weeks in the remaining 12 survivors.
This syndrome is not uncommon and should be considered particularly in female patients presenting with acute myocardial infarction.
左心室心尖部气球样变是日本最近描述的一种新综合征，其特征为胸痛、类似急性心肌梗死的心电图改变以及冠状动脉正常情况下的短暂心尖部运动障碍。尽管多项研究已明确该综合征的临床特征，但其患病率仍不明确。
本研究旨在确定左心室心尖部气球样变综合征的患病率。
2002年1月至2004年9月，从连续638例因初次经皮冠状动脉介入治疗而转诊至我院心脏研究所的患者中收集住院及随访的临床、超声心动图和血管造影数据。
13例患者（2%）被诊断为短暂性左心室心尖部气球样变。除1例患者外均为女性，在急性心肌梗死女性患者中的发病率为6%。8例患者发现了诱发因素。1例患者死于心源性休克。其余12例幸存者的左心室收缩功能在4 - 5周内完全恢复。
该综合征并不罕见，对于表现为急性心肌梗死的女性患者应特别予以考虑。
