英格兰东北部泰恩赛德北部一个地区帕金森病的患病率。
The prevalence of Parkinson's disease in an area of North Tyneside in the North-East of England.
作者信息
Porter Bob, Macfarlane Rob, Unwin Nigel, Walker Richard
机构信息
Parkinson's Disease Service, Northumbria Healthcare NHS Trust, Tyne and Wear, Newcastle upon Tyne, UK.
出版信息
Neuroepidemiology. 2006;26(3):156-61. doi: 10.1159/000091657. Epub 2006 Feb 21.
OBJECTIVES
UK prevalence studies have demonstrated prevalence rates for Parkinson's disease (PD) of 108 to 164 cases per 100,000. we aimed to calculate the prevalence of PD in an area of the North-East of England.
MATERIAL AND METHODS
A case finding methodology was used to identify cases in North Tyneside with a population of 108,597 at the 2001 UK census.
RESULTS
161 cases were identified giving crude and age-adjusted prevalence estimates of 148 cases (95% CI 124-174) and 139 cases (95% CI 116-162) per 100,000, respectively. The mean age was 74.1 years (range 44-96 years) with mean disease duration of 5.6 years.
CONCLUSIONS
The prevalence of PD in North Tyneside is comparable with that of the rest of the UK. The prevalence of PD in the UK appears not to have changed greatly over the last 30 years.
目的
英国的患病率研究表明，帕金森病（PD）的患病率为每10万人中有108至164例。我们旨在计算英格兰东北部一个地区的PD患病率。
材料与方法
采用病例发现方法，在2001年英国人口普查中识别泰恩赛德北部地区的病例，该地区人口为108,597人。
结果
共识别出161例病例，粗患病率和年龄调整患病率估计分别为每10万人中有148例（95%置信区间124 - 174）和139例（95%置信区间116 - 162）。平均年龄为74.1岁（范围44 - 96岁），平均病程为5.6年。
结论
泰恩赛德北部地区的PD患病率与英国其他地区相当。在过去30年里，英国PD的患病率似乎没有太大变化。
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