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蛋白质语言学——模块化蛋白质组装的语法规则?

Protein linguistics - a grammar for modular protein assembly?

作者信息

Gimona Mario

机构信息

Consorzio Mario Negri Sud, Marie Curie Unit of Actin Cytoskeleton Regulation, Department of Cell Biology and Oncology, Via Nazionale 8A, 66030 Santa Maria Imbaro, Italy.

出版信息

Nat Rev Mol Cell Biol. 2006 Jan;7(1):68-73. doi: 10.1038/nrm1785.

Abstract

The correspondence between biology and linguistics at the level of sequence and lexical inventories, and of structure and syntax, has fuelled attempts to describe genome structure by the rules of formal linguistics. But how can we define protein linguistic rules? And how could compositional semantics improve our understanding of protein organization and functional plasticity?

摘要

生物学与语言学在序列和词汇表层面以及结构和句法层面的对应关系,激发了人们用形式语言学规则来描述基因组结构的尝试。但是我们如何定义蛋白质语言规则呢?组合语义学又如何能增进我们对蛋白质组织和功能可塑性的理解呢?

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